Fisher G C, Hutton P
University of Birmingham, Queen Elizabeth Hospital, Edgbaston.
Anaesthesia. 1989 Feb;44(2):104-6. doi: 10.1111/j.1365-2044.1989.tb11155.x.
Patients who underwent peripheral arterial surgery had anaesthesia maintained with an infusion of midazolam. They were allowed either to recover spontaneously or to have the effects of midazolam reversed by flumazenil at the end of surgery. This study demonstrated that the cardiovascular responses to arousal using flumazenil are no different from those seen when the patient is allowed to recover in the normal way. This result has obvious advantages for clinical practice but the dangers of resedation must not be forgotten.
接受外周动脉手术的患者通过输注咪达唑仑维持麻醉。他们可以选择自然恢复，或者在手术结束时使用氟马西尼逆转咪达唑仑的作用。这项研究表明，使用氟马西尼唤醒时的心血管反应与患者以正常方式恢复时所见的反应没有差异。这一结果对临床实践具有明显优势，但再次镇静的风险也不容忽视。
