Internal Medicine and Gastroenterology Department, Cairo University, Egypt.
National Hepatology and Tropical Medicine Research Institute (NHTMRI); Assiut, Egypt.
Endosc Ultrasound. 2013 Oct;2(4):190-3. doi: 10.4103/2303-9027.121239.
Pancreatic carcinoma is one of the leading cancer morbidity and mortality world-wide. Controversy has arisen about whether the percutaneous approach with computed tomography/ultrasonography-guidance fine needle aspiration (US-FNA) or endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is the preferred method to obtain diagnostic tissue. Our purpose of this study is to compare between the diagnostic accuracy of EUS-FNA and percutaneous US-FNA in diagnosis of pancreatic cancer.
A total of 197 patients with pancreatic masses were included in the study, 125 patients underwent US-FNA (Group 1) and 72 patients underwent EUS-FNA (Group 2).
EUS-FNA has nearly the same accuracy (88.9%) as US-FNA (87.2%) in diagnosis of pancreatic cancer. The sensitivity, specificity, positive predictive value and negative predictive value for EUS-FNA was 84%, 100%, 100%, 73.3% respectively. It was 85.5%, 90.4%, 94.7%, 76% respectively for US-FNA. EUS-FNA had a lower complication rate (1.38%) than US-FNA (5.6%).
EUS-FNA has nearly the same accuracy as US-FNA of pancreatic masses with a lower complication rate.
胰腺癌是全球主要的癌症发病率和死亡率之一。关于经皮方法（计算机断层扫描/超声引导下细针抽吸术[US-FNA]或内镜超声引导下细针抽吸术[EUS-FNA]）是否是获取诊断性组织的首选方法，存在争议。本研究旨在比较 EUS-FNA 和经皮 US-FNA 对胰腺癌诊断的准确性。
共有 197 名胰腺肿块患者纳入本研究，其中 125 名患者接受 US-FNA（第 1 组），72 名患者接受 EUS-FNA（第 2 组）。
EUS-FNA 在诊断胰腺癌方面的准确性与 US-FNA（87.2%）几乎相同（88.9%）。EUS-FNA 的敏感性、特异性、阳性预测值和阴性预测值分别为 84%、100%、100%、73.3%。US-FNA 的敏感性、特异性、阳性预测值和阴性预测值分别为 85.5%、90.4%、94.7%、76%。EUS-FNA 的并发症发生率（1.38%）低于 US-FNA（5.6%）。
EUS-FNA 对胰腺肿块的准确性与 US-FNA 几乎相同，但其并发症发生率较低。
