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膳食补充超氧化物歧化酶-甜瓜浓缩物可减轻健康人群的压力和身心疲劳:一项随机、双盲、安慰剂对照试验。

Dietary supplementation with a superoxide dismutase-melon concentrate reduces stress, physical and mental fatigue in healthy people: a randomised, double-blind, placebo-controlled trial.

机构信息

Bionov Company, 939 rue de la Croix Verte, Montpellier 34090, France.

Seppic Company, 22 Terasse Bellini, Puteaux 92806, France.

出版信息

Nutrients. 2014 Jun 19;6(6):2348-59. doi: 10.3390/nu6062348.

DOI:10.3390/nu6062348
PMID:24949549
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4073155/
Abstract

BACKGROUND

We aimed to investigate effects of superoxide dismutase (SOD)-melon concentrate supplementation on psychological stress, physical and mental fatigue in healthy people.

METHODS

A randomized, double-blind, placebo-controlled trial was performed on 61 people divided in two groups: active supplement (n = 32) and placebo (n = 29) for 12 weeks. Volunteers were given one small hard capsule per day. One capsule contained 10 mg of SOD-melon concentrate (140 U of SOD) and starch for the active supplement and starch only for the placebo. Stress and fatigue were evaluated using four psychometric scales: PSS-14; SF-36; Stroop tests and Prevost scale.

RESULTS

The supplementation with SOD-melon concentrate significantly decreased perceived stress, compared to placebo. Moreover, quality of life was improved and physical and mental fatigue were reduced with SOD-melon concentrate supplementation.

CONCLUSION

SOD-melon concentrate supplementation appears to be an effective and natural way to reduce stress and fatigue.

TRIAL REGISTRATION

trial approved by the ethical committee of Poitiers (France), and the ClinicalTrials.gov Identifier is NCT01767922.

摘要

背景

我们旨在研究超氧化物歧化酶(SOD)-甜瓜浓缩物补充剂对健康人群心理压力、身心疲劳的影响。

方法

对 61 名志愿者进行了一项随机、双盲、安慰剂对照试验,将他们分为两组:活性补充剂(n = 32)和安慰剂(n = 29),持续 12 周。志愿者每天服用一粒小硬胶囊。活性补充剂中的一粒胶囊含有 10 毫克 SOD-甜瓜浓缩物(140U SOD)和淀粉,安慰剂中只含有淀粉。使用四个心理计量表评估压力和疲劳:PSS-14;SF-36;斯特鲁普测试和普雷沃量表。

结果

与安慰剂相比,SOD-甜瓜浓缩物补充剂显著降低了感知压力。此外,SOD-甜瓜浓缩物补充剂还改善了生活质量,减轻了身心疲劳。

结论

SOD-甜瓜浓缩物补充剂似乎是一种有效且自然的减轻压力和疲劳的方法。

试验注册

该试验得到了普瓦捷(法国)伦理委员会的批准,ClinicalTrials.gov 标识符为 NCT01767922。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9e/4073155/598676c13230/nutrients-06-02348-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9e/4073155/71ab0c010de3/nutrients-06-02348-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9e/4073155/c26ccdc3cb09/nutrients-06-02348-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9e/4073155/70faec8c074f/nutrients-06-02348-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9e/4073155/598676c13230/nutrients-06-02348-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9e/4073155/71ab0c010de3/nutrients-06-02348-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9e/4073155/c26ccdc3cb09/nutrients-06-02348-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9e/4073155/70faec8c074f/nutrients-06-02348-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c9e/4073155/598676c13230/nutrients-06-02348-g004.jpg

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