一例极晚期默克尔细胞癌完全自发消退的病例。

Sugamata A, Goya K, Yoshizawa N

Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.

J Surg Case Rep. 2011 Oct 1;2011(10):7. doi: 10.1093/jscr/2011.10.7.

Merkel cell carcinoma (MCC) is a rare locally malignant cutaneous tumor of neuroendocrine origin, most often occurring on the head and neck of the elderly. MCC is a highly aggressive tumor with a high percentage of recurrence, metastatic spread and mortality. Despite the highly malignant course of MCC, there have been several reports of spontaneous regression or resolution. We report the clinical course of a 71-year-old man with MCC. The tumor initially occurred in the left lower eyelid and advanced to encompass nearly half the face. Despite its large size, complete spontaneous regression of the tumor occurred. This is the most advanced case of complete spontaneous regression of MCC to be reported.

默克尔细胞癌（MCC）是一种罕见的起源于神经内分泌的局部恶性皮肤肿瘤，最常发生于老年人的头颈部。MCC是一种侵袭性很强的肿瘤，复发、转移扩散和死亡率很高。尽管MCC病程高度恶性，但仍有几例自发消退或缓解的报道。我们报告一名71岁男性MCC患者的临床病程。肿瘤最初发生于左下眼睑，进展后几乎累及半张脸。尽管肿瘤体积很大，但仍发生了完全自发消退。这是报道的MCC完全自发消退最严重的病例。