Zuliani U, Bernardini B, Catapano A, Campana M, Cerioli G, Spattini M
Cattedra di Medicina dello Sport, University of Parma, Italy.
Int J Sports Med. 1989 Feb;10(1):62-6. doi: 10.1055/s-2007-1024877.
To evaluate the metabolic or cardiovascular effects induced by self-administration of human growth hormone (HGH) alone or combined with testosterone and anabolic steroids, we conducted a study with 15 male body builders. Of these, 8 (control group) did not take any hormonal substances; 6 (experimental group) self-administered testosterone, anabolic steroids, and HGH for 6 weeks in various dosages; 1 subject self-administered only HGH for an equal period of time. At the end of the period of treatment with the hormonal combination, the experimental group continued for 2 additional weeks with anabolic steroids and testosterone only. All maintained the same, unaltered type and intensity of training, and constant diet. Before the beginning of treatment with hormonal substances, after 6 weeks, and at the end of treatment (for a total of 8 weeks), they were tested for total and HDL-cholesterol (t-chol and HDL-chol), apolipoproteins A-1 and B (apo A-1 and B), and triglycerides (tg). Before the start and after 6 weeks, an echocardiographic examination was performed to assess left ventricular dimensions and function in all 15 body builders. The most interesting result is a significant decrease of HDL-chol and apo A-1 derived from self-administration of anabolic steroids and HGH together.
为了评估单独自行使用人生长激素（HGH）或与睾酮及合成代谢类固醇联合使用所引发的代谢或心血管效应，我们对15名男性健美运动员进行了一项研究。其中，8人（对照组）未服用任何激素类物质；6人（实验组）以不同剂量自行服用睾酮、合成代谢类固醇和HGH，为期6周；1名受试者仅自行服用HGH相同时长。在使用激素组合治疗期结束时，实验组仅继续使用合成代谢类固醇和睾酮2周。所有人均维持相同、未改变的训练类型和强度以及固定饮食。在开始使用激素类物质治疗前、6周后以及治疗结束时（总共8周），对他们进行了总胆固醇和高密度脂蛋白胆固醇（总胆固醇和HDL - 胆固醇）、载脂蛋白A - 1和B（载脂蛋白A - 1和B）以及甘油三酯（甘油三酯）的检测。在开始前和6周后，对所有15名健美运动员进行了超声心动图检查，以评估左心室大小和功能。最有趣的结果是，同时自行服用合成代谢类固醇和HGH会使HDL - 胆固醇和载脂蛋白A - 1显著降低。
