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橄榄果实/橄榄油通过调节抗氧化、抗肿瘤和基因活性在疾病预防中的治疗作用。

Therapeutics role of olive fruits/oil in the prevention of diseases via modulation of anti-oxidant, anti-tumour and genetic activity.

作者信息

Rahmani Arshad H, Albutti Aqel S, Aly Salah M

机构信息

Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University Saudi Arabia.

Department of Medical Biotechnology, Fac. of Applied Med. Sciences, Qassim University Saudi Arabia.

出版信息

Int J Clin Exp Med. 2014 Apr 15;7(4):799-808. eCollection 2014.

Abstract

The current mode of treatment for various diseases is based on synthetic drugs are effective but they show adverse effect and also alter the genetic and metabolic activity. Moreover, some drugs prepared from plants and their constituents show potentiality with more efficacy than synthetic agents used in clinical therapy. Earlier report has shown that regular consumption of fruits and vegetables is strongly related with reduced risk of developing various diseases. Several epidemiological studies has shown that, the incidence heart disease and cancers is lowest in the Mediterranean basin as compared to the part of the world because of their diet rich in olives and olive products. Olives are commonly consumed in Mediterranean and Arabian Peninsula and also have been documented in Holy Quran and modern scientific literatures. Earlier studies have shown that, the constituents from olive such as oleuropein, squalene and hydroxytyrosol modulate the genes functions and other activities. In this review, the medicinal value of olives and their constituents are summarized in terms of therapeutic approach in the diseases management through regulation of various activities.

摘要

目前各种疾病的治疗模式基于合成药物,这些药物虽有效,但会产生副作用,还会改变基因和代谢活动。此外,一些由植物及其成分制备的药物显示出比临床治疗中使用的合成药物更有效的潜力。早期报告表明,经常食用水果和蔬菜与降低患各种疾病的风险密切相关。多项流行病学研究表明,与世界其他地区相比,地中海地区因富含橄榄和橄榄制品的饮食,心脏病和癌症的发病率最低。橄榄在地中海和阿拉伯半岛普遍食用,在《古兰经》和现代科学文献中也有记载。早期研究表明,橄榄中的成分如橄榄苦苷、角鲨烯和羟基酪醇可调节基因功能和其他活动。在这篇综述中,橄榄及其成分的药用价值通过调节各种活动在疾病管理中的治疗方法进行了总结。

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