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一项关于干燥综合征患者口腔状况的描述性研究。

A descriptive study of the oral status in subjects with Sjögren's syndrome.

作者信息

Olate Sergio, Muñoz Daniella, Neumann Stephanie, Pozzer Leandro, Cavalieri-Pereira Lucas, de Moraes Márcio

机构信息

Division of Oral and Maxillofacial Surgery, Universidad de La Frontera Chile ; Center for Biomedical Research, Universidad Autónoma de Chile Chile.

Division of Oral and Maxillofacial Surgery, Universidad de La Frontera Chile.

出版信息

Int J Clin Exp Med. 2014 Apr 15;7(4):1140-4. eCollection 2014.

Abstract

Sjögren's Syndrome (SS) is an autoimmune pathology of varying prevalence. Its involvement in exocrine glands requires that greater attention be paid to patients' oral health. A cross-sectional study was designed to assess the oral health of subjects with SS in constant medical follow-ups. Variables such as the presence of periodontal infections, decay and alterations in the oral mucosa were analyzed, and the individual's salivary flow was measured. The data were analyzed descriptively and with the chi-squared test, considering p<0.05 as statistically significant. 35 subjects of both sexes were studied, aged between 25 and 82 years, with an age average of 53.9 years; they presented on average 7.9 years after the initial diagnosis. The subjects reported a dental check-up every 6 months in only 9% of cases, whereas the rest had one every 1 or 2 years. All the subjects recounted presenting with dry mouth and associated significantly the ingestion of fluids and teeth brushing to improve the sensation of dryness. The salivary flow was objectively seen to be compromised, showing a significant reduction in those with more time since diagnosis of the disease; more than 90% of subjects exhibited periodontal inflammation and a high level of caries. The mucosa presented a low level of pathology. In conclusion, education in oral health is imperative for subjects with this pathology and more frequent check-ups may be useful in decreasing the levels of oral pathology.

摘要

干燥综合征(SS)是一种患病率各异的自身免疫性疾病。其对唾液腺的影响要求更加关注患者的口腔健康。一项横断面研究旨在评估处于持续医学随访中的干燥综合征患者的口腔健康状况。分析了诸如牙周感染、龋齿及口腔黏膜病变等变量,并测量了个体的唾液流量。对数据进行了描述性分析,并采用卡方检验,将p<0.05视为具有统计学意义。共研究了35名男女受试者,年龄在25岁至82岁之间,平均年龄为53.9岁;他们在初次诊断后平均7.9年。只有9%的受试者报告每6个月进行一次牙科检查,而其余受试者每1年或2年进行一次检查。所有受试者都诉说有口干症状,并显著提及通过摄入液体和刷牙来改善干燥感。客观上观察到唾液流量受到影响,自疾病诊断后时间越长的患者唾液流量显著降低;超过90%的受试者表现出牙周炎症和高龋齿率。黏膜病变程度较低。总之,对于患有这种疾病的患者,口腔健康教育势在必行,更频繁的检查可能有助于降低口腔病变水平。

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