Yang Kun, Zhou Yun, Ren Qiushi, Ye Jing Yong, Deng Cheri X
Department of Biomedical Engineering, University of Michigan, 2200 Bonisteel Boulevard, Ann Arbor, Michigan 48109, USA ; Department of Biomedical Engineering, Shanghai Jiaotong University, 800 Dongchuan Road, Shanghai 200240, People's Republic of China.
Department of Biomedical Engineering, University of Michigan, 2200 Bonisteel Boulevard, Ann Arbor, Michigan 48109, USA.
Appl Phys Lett. 2009 Aug 3;95(5):051107. doi: 10.1063/1.3187535. Epub 2009 Aug 6.
Different from conventional optical tweezers used for trapping high refractive index micron-sized particles, bubble generation and trapping by femtosecond laser offer a unique strategy to manipulate microbubbles. Using high frequency ultrasound imaging and fast-frame optical video microscopy, we obtained results revealing the spatiotemporal characteristics of bubble generation and trapping by self-focused femtosecond laser pulses at multiple locations along the laser beam. We detected distinct acoustic signals associated with the laser focus and measured the trapping force by using acoustic radiation force to detrap the bubble from the laser beam.
与用于捕获高折射率微米级粒子的传统光镊不同，飞秒激光产生和捕获气泡提供了一种操纵微气泡的独特策略。利用高频超声成像和快速帧光学视频显微镜，我们获得了揭示沿激光束多个位置的自聚焦飞秒激光脉冲产生和捕获气泡的时空特性的结果。我们检测到与激光焦点相关的独特声信号，并通过使用声辐射力将气泡从激光束中解捕获来测量捕获力。
