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酒精中毒中的神经递质:神经生物学与遗传学研究综述

Neurotransmitters in alcoholism: A review of neurobiological and genetic studies.

作者信息

Banerjee Niladri

机构信息

Amity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, India.

出版信息

Indian J Hum Genet. 2014 Jan;20(1):20-31. doi: 10.4103/0971-6866.132750.

Abstract

Recent advances in the study of alcoholism have thrown light on the involvement of various neurotransmitters in the phenomenon of alcohol addiction. Various neurotransmitters have been implicated in alcohol addiction due to their imbalance in the brain, which could be either due to their excess activity or inhibition. This review paper aims to consolidate and to summarize some of the recent papers which have been published in this regard. The review paper will give an overview of the neurobiology of alcohol addiction, followed by detailed reviews of some of the recent papers published in the context of the genetics of alcohol addiction. Furthermore, the author hopes that the present text will be found useful to novices and experts alike in the field of neurotransmitters in alcoholism.

摘要

酒精中毒研究的最新进展揭示了各种神经递质在酒精成瘾现象中的作用。由于大脑中神经递质失衡,各种神经递质与酒精成瘾有关,这种失衡可能是由于它们的过度活动或抑制。这篇综述文章旨在整合和总结近期在这方面发表的一些论文。该综述文章将概述酒精成瘾的神经生物学,随后详细综述一些在酒精成瘾遗传学背景下发表的近期论文。此外,作者希望本文对酒精中毒领域神经递质方面的新手和专家都有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b312/4065474/89a8fe154ffd/IJHG-20-20-g001.jpg

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