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自动血液学分析仪在间日疟诊断中的应用：传统显微镜检查的辅助手段

Automated Hematology Analyzers in Diagnosis of Plasmodium vivax Malaria: an Adjunct to Conventional Microscopy.

作者信息

Mubeen Kolakkadan Hasaf, Devadoss Clement Wilfred, Rangan Rau Aarathi, Gitanjali Monnappa, Prasanna Shetty, Sunitha Vp

机构信息

Department of Pathology, M.S Ramaiah Medical College & Teaching Hospital, Bangalore. India.

出版信息

Mediterr J Hematol Infect Dis. 2014 Jun 1;6(1):e2014034. doi: 10.4084/MJHID.2014.034. eCollection 2014.

DOI:10.4084/MJHID.2014.034
PMID:24959331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4063614/
Abstract

Malaria is one of the most pervasive parasitic diseases ever known to mankind affecting nearly 300 million people every year. The need for rapid diagnosis of malaria in tropical and subtropical malaria endemic areas is on the rise. In this study, we evaluated the usefulness of hematology autoanalyzers, Sysmex XE-2100 & XT-2000i in the presumptive diagnosis of malaria. Our study shows that abnormalities in WBC/BASO scattergram when combined with presence of thrombocytopenia had a high sensitivity and positive predictive value in the presumptive diagnosis of Plasmodium vivax (P.vivax) malaria.

摘要

疟疾是人类已知的最普遍的寄生虫病之一，每年影响近3亿人。热带和亚热带疟疾流行地区对疟疾快速诊断的需求正在上升。在本研究中，我们评估了血液学自动分析仪Sysmex XE - 2100和XT - 2000i在疟疾初步诊断中的实用性。我们的研究表明，白细胞/嗜碱性粒细胞散点图异常与血小板减少症同时出现时，对间日疟原虫疟疾的初步诊断具有较高的敏感性和阳性预测值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba01/4063614/2c192a62d3c6/mjhid-6-1-e2014034f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba01/4063614/c91670f91b73/mjhid-6-1-e2014034f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba01/4063614/d47ef2aa0c28/mjhid-6-1-e2014034f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba01/4063614/aa473c272fb6/mjhid-6-1-e2014034f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba01/4063614/70b5f6df76aa/mjhid-6-1-e2014034f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba01/4063614/2c192a62d3c6/mjhid-6-1-e2014034f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba01/4063614/c91670f91b73/mjhid-6-1-e2014034f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba01/4063614/d47ef2aa0c28/mjhid-6-1-e2014034f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba01/4063614/aa473c272fb6/mjhid-6-1-e2014034f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba01/4063614/70b5f6df76aa/mjhid-6-1-e2014034f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba01/4063614/2c192a62d3c6/mjhid-6-1-e2014034f5.jpg

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本文引用的文献

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2
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Indian J Pathol Microbiol. 2012 Oct-Dec;55(4):467-73. doi: 10.4103/0377-4929.107782.
3
Performance of two rapid diagnostic tests for malaria diagnosis at the China-Myanmar border area.
Sysmex XN-31 荧光流式细胞术在非流行地区诊断输入性疟疾的准确性。
Parasite. 2022;29:31. doi: 10.1051/parasite/2022031. Epub 2022 May 31.
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Pak J Med Sci. 2022 Mar-Apr;38(3Part-I):687-691. doi: 10.12669/pjms.38.3.4702.
中缅边境地区两种疟疾快速诊断检测试剂的性能比较。
Malar J. 2013 Feb 22;12:73. doi: 10.1186/1475-2875-12-73.
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