Kondo M, Tsuchiya K
Antimicrob Agents Chemother. 1978 Jul;14(1):151-3. doi: 10.1128/AAC.14.1.151.
The in vivo activities of cefsulodin, sulbenicillin, and gentamicin were compared in mice infected intraperitoneally with Pseudomonas aeruginosa. In mice infected with sulbenicillin- and gentamicin-susceptible strains, cefsulodin was about 12 to 60 times more active than sulbenicillin and had an activity similar to gentamicin. In mice, the activity of cefsulodin was independent whether the strains were resistant to gentamicin or not, but it was considerably affected by resistance of the strains to sulbenicillin.
在腹腔感染铜绿假单胞菌的小鼠体内比较了头孢磺啶、磺苄西林和庆大霉素的活性。在感染对磺苄西林和庆大霉素敏感菌株的小鼠中，头孢磺啶的活性比磺苄西林高约12至60倍，且与庆大霉素的活性相似。在小鼠中，头孢磺啶的活性不受菌株是否对庆大霉素耐药的影响，但受菌株对磺苄西林耐药性的显著影响。
