头孢磺啶、磺苄西林和庆大霉素对铜绿假单胞菌的体内比较活性
Comparative in vivo activities of cefsulodin, sulbenicillin, and gentamicin against Pseudomonas aeruginosa.
作者信息
Kondo M, Tsuchiya K
出版信息
Antimicrob Agents Chemother. 1978 Jul;14(1):151-3. doi: 10.1128/AAC.14.1.151.
Abstract
The in vivo activities of cefsulodin, sulbenicillin, and gentamicin were compared in mice infected intraperitoneally with Pseudomonas aeruginosa. In mice infected with sulbenicillin- and gentamicin-susceptible strains, cefsulodin was about 12 to 60 times more active than sulbenicillin and had an activity similar to gentamicin. In mice, the activity of cefsulodin was independent whether the strains were resistant to gentamicin or not, but it was considerably affected by resistance of the strains to sulbenicillin.
摘要
在腹腔感染铜绿假单胞菌的小鼠体内比较了头孢磺啶、磺苄西林和庆大霉素的活性。在感染对磺苄西林和庆大霉素敏感菌株的小鼠中，头孢磺啶的活性比磺苄西林高约12至60倍，且与庆大霉素的活性相似。在小鼠中，头孢磺啶的活性不受菌株是否对庆大霉素耐药的影响，但受菌株对磺苄西林耐药性的显著影响。
相似文献
1
Comparative in vivo activities of cefsulodin, sulbenicillin, and gentamicin against Pseudomonas aeruginosa.头孢磺啶、磺苄西林和庆大霉素对铜绿假单胞菌的体内比较活性
Antimicrob Agents Chemother. 1978 Jul;14(1):151-3. doi: 10.1128/AAC.14.1.151.
2
Comparative in vitro activities of SCE-129, sulbenicillin, gentamicin, and dibekacin against Pseudomonas.SCE - 129、磺苄西林、庆大霉素和地贝卡星对假单胞菌的体外比较活性
Antimicrob Agents Chemother. 1978 Mar;13(3):536-9. doi: 10.1128/AAC.13.3.536.
3
Combined action of sulbenicillin and gentamicin.
J Antibiot (Tokyo). 1974 Mar;27(3):199-205. doi: 10.7164/antibiotics.27.199.
4
Comparative studies of cefotaxime and sulbenicillin in complicated urinary tract infections.头孢噻肟与磺苄西林治疗复杂性尿路感染的对照研究。
J Antimicrob Chemother. 1980 Sep;6 Suppl A:213-8. doi: 10.1093/jac/6.suppl_a.213.
5
Bacteriological studies on the combined action of aminoglycoside antibiotics and synthetic penicillins against Pseudomonas aeruginosa.氨基糖苷类抗生素与合成青霉素联合作用对铜绿假单胞菌的细菌学研究
J Antibiot (Tokyo). 1974 Dec;27(12):989-91. doi: 10.7164/antibiotics.27.989.
6
Gentamicin and cefsulodin efficacy in a rat abscess model.庆大霉素和头孢磺啶在大鼠脓肿模型中的疗效。
Surg Gynecol Obstet. 1982 Sep;155(3):363-8.
7
[Susceptibility of Pseudomonas aeruginosa recently isolated from clinical specimens to various antimicrobial agents and changes of susceptibility to carbenicillin, gentamicin and amikacin (author's transl)].[近期从临床标本中分离出的铜绿假单胞菌对各种抗菌剂的敏感性以及对羧苄青霉素、庆大霉素和丁胺卡那霉素敏感性的变化（作者译）]
Jpn J Antibiot. 1980 Jun;33(6):668-74.
8
Resistance to cefsulodin and gentamicin in Pseudomonas aeruginosa strains in five areas of Japan between 1980 and 1983.1980年至1983年间日本五个地区铜绿假单胞菌菌株对头孢磺啶和庆大霉素的耐药性
J Antimicrob Chemother. 1986 Jun;17(6):755-62. doi: 10.1093/jac/17.6.755.
9
[Clinical investigation of combined therapy (cefotiam, sulbenicillin and cefsulodin) against infections complicated by acute leukemia].
Jpn J Antibiot. 1983 Jan;36(1):71-5.
10
[Morphology of Pseudomonas aeruginosa altered by antibiotic effect of sulbenicillin].[磺苄西林抗生素作用对铜绿假单胞菌形态的影响]
Nihon Saikingaku Zasshi. 1977 Mar;32(2):337-43.
引用本文的文献
1
Single-dose pharmacokinetics of cefsulodin in patients with cystic fibrosis.头孢磺啶在囊性纤维化患者中的单剂量药代动力学。
Antimicrob Agents Chemother. 1984 May;25(5):579-81. doi: 10.1128/AAC.25.5.579.
2
Antibiotic pharmacokinetics in cystic fibrosis. Differences and clinical significance.囊性纤维化患者的抗生素药代动力学。差异及临床意义。
Clin Pharmacokinet. 1987 Oct;13(4):228-53. doi: 10.2165/00003088-198713040-00002.
3
SCE-963, a new broad-spectrum cephalosporin: in vitro and in vivo antibacterial activities.SCE - 963，一种新型广谱头孢菌素：体外及体内抗菌活性
Antimicrob Agents Chemother. 1978 Oct;14(4):557-68. doi: 10.1128/AAC.14.4.557.
本文引用的文献
1
Ototoxicity of tobramycin in guinea pigs.妥布霉素对豚鼠的耳毒性。
Arch Otolaryngol. 1971 Jul;94(1):59-63. doi: 10.1001/archotol.1971.00770070095011.
2
Antibiotic 6640. 3. Biological studies with antibiotic 6640, a new broad-spectrum aminoglycoside antibiotic.抗生素6640。3. 新型广谱氨基糖苷类抗生素6640的生物学研究。
J Antibiot (Tokyo). 1970 Nov;23(11):559-65.
3
Cross-resistance of Pseudomonas to gentamicin and tobramycin.铜绿假单胞菌对庆大霉素和妥布霉素的交叉耐药性。
Antimicrob Agents Chemother. 1972 Mar;1(3):280-1. doi: 10.1128/AAC.1.3.280.
4
BB-K 8, a new semisynthetic aminoglycoside antibiotic.
J Antibiot (Tokyo). 1972 Dec;25(12):695-708. doi: 10.7164/antibiotics.25.695.
5
PC-904, a novel broad-spectrum semisynthetic penicillin with marked antipseudomonal activity: microbiological evaluation.PC-904，一种新型的具有显著抗假单胞菌活性的广谱半合成青霉素：微生物学评价
Antimicrob Agents Chemother. 1976 Feb;9(2):262-73. doi: 10.1128/AAC.9.2.262.
6
Laboratory studies with a new broad-spectrum penicillin, pirbenicillin.使用新型广谱青霉素匹氨西林进行的实验室研究。
Antimicrob Agents Chemother. 1976 Jun;9(6):975-82. doi: 10.1128/AAC.9.6.975.
7
In vitro and in vivo antibacterial activity of T-1220, a new semisynthetic penicillin.新型半合成青霉素T-1220的体外及体内抗菌活性
Antimicrob Agents Chemother. 1977 Oct;12(4):455-60. doi: 10.1128/AAC.12.4.455.
8
Mezlocillin: in vitro studies of a new broad-spectrum penicillin.美洛西林：一种新型广谱青霉素的体外研究
Antimicrob Agents Chemother. 1977 Jan;11(1):74-9. doi: 10.1128/AAC.11.1.74.
9
Bactericidal efficacy of Sch 20569 and amikacin against gentamicin-sensitive and -resistant organisms.Sch 20569和阿米卡星对庆大霉素敏感及耐药菌的杀菌效力
Antimicrob Agents Chemother. 1976 Apr;9(4):595-9. doi: 10.1128/AAC.9.4.595.
10
SCE-129, antipseudomonal cephalosporin: in vitro and in vivo antibacterial activities.SCE - 129，抗假单胞菌头孢菌素：体外和体内抗菌活性
Antimicrob Agents Chemother. 1978 Feb;13(2):137-45. doi: 10.1128/AAC.13.2.137.
Zotero 插件