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原发性脊柱硬膜外霍奇金淋巴瘤。

Primary spinal epidural Hodgkin's lymphoma.

作者信息

Yaman Onur, Ozdemir Nail, Sevin Ismail Ertan, Ozer Füsun Demirçivi, Unlüoğlu Saime

机构信息

Tepecik Education and Training Hospital, Clinic of Neurosurgery, Neurosurgeon, İzmir, Turkey

Tepecik Education and Training Hospital, Clinic of Neurosurgery, Neurosurgeon, İzmir, Turkey.

出版信息

J Surg Case Rep. 2013 Oct 22;2013(10):rjt090. doi: 10.1093/jscr/rjt090.

DOI:10.1093/jscr/rjt090
PMID:24964329
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3853234/
Abstract

Primary spinal epidural Hodgkin's lymphoma is very rare. We will discuss the clinical features and treatment of primary spinal epidural Hodgkin's lymphoma. In this paper, a 30-year-old male patient who presented with spinal epidural tumor at the T9-11 level is reported. Subtotal resection of the tumor was performed and the histological examination of the tumor specimen revealed Hodgkin's lymphoma. All other examinations were negative for an occult disease. Six courses of chemotheraphy containing adriamycin, bleomycin, vinblastine and dacarbazine were given to the patient. Surgery is the first therapeutic approach in malignancies compressing the spinal cord. Hodgkin's lymphoma is a very chemo- and radio-sensitive tumor. The indications for surgery were reduced and limited to laminectomy or even biopsy only, leaving the major role to chemo- and radiotheraphy.

摘要

原发性脊柱硬膜外霍奇金淋巴瘤非常罕见。我们将讨论原发性脊柱硬膜外霍奇金淋巴瘤的临床特征及治疗方法。本文报道了一名30岁男性患者,其在T9 - 11水平出现脊柱硬膜外肿瘤。对肿瘤进行了次全切除,肿瘤标本的组织学检查显示为霍奇金淋巴瘤。所有其他检查均未发现隐匿性疾病。给予该患者六个疗程包含阿霉素、博来霉素、长春花碱和达卡巴嗪的化疗。手术是治疗压迫脊髓的恶性肿瘤的首要治疗方法。霍奇金淋巴瘤是一种对化疗和放疗非常敏感的肿瘤。手术指征减少,仅限于椎板切除术甚至仅活检,主要治疗作用留给化疗和放疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb6/3853234/dd6fceb7e265/rjt09005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb6/3853234/3b50309305d8/rjt09001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb6/3853234/9e50d551a993/rjt09002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb6/3853234/528382a9cd47/rjt09003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb6/3853234/1559567b9d83/rjt09004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb6/3853234/dd6fceb7e265/rjt09005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb6/3853234/3b50309305d8/rjt09001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb6/3853234/9e50d551a993/rjt09002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb6/3853234/528382a9cd47/rjt09003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb6/3853234/1559567b9d83/rjt09004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb6/3853234/dd6fceb7e265/rjt09005.jpg

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本文引用的文献

1
Isolated, primary spinal epidural Hodgkin's disease in a child.一名儿童的孤立性原发性脊柱硬膜外霍奇金淋巴瘤。
Pediatr Neurol. 2009 Jun;40(6):480-2. doi: 10.1016/j.pediatrneurol.2009.01.006.
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Cervical radiculopathy secondary to Hodgkin's lymphoma.继发于霍奇金淋巴瘤的颈神经根病
Surg Neurol. 2007 May;67(5):540-3. doi: 10.1016/j.surneu.2006.08.071.
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Primary spinal extranodal Hodgkin's disease at two levels.两级原发性脊柱结外霍奇金淋巴瘤
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