Centanni Manuela, Turroni Silvia, Rampelli Simone, Biagi Elena, Quercia Sara, Consolandi Clarissa, Severgnini Marco, Brigidi Patrizia, Candela Marco
Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
FEMS Microbiol Lett. 2014 Aug;357(2):157-63. doi: 10.1111/1574-6968.12515. Epub 2014 Jul 14.
Using a previously developed in vitro model to characterize the enterocyte-adherent microbiota fraction, we explored the potential of the probiotic strain Bifidobacterium animalis ssp. lactis BI07 to modulate the inflammation-dependent dysbioses of the enterocyte-adherent microbiota from 12 healthy human donors. According to our findings, B. animalis ssp. lactis BI07 is effective in limiting the increase of pro-inflammatory pathobionts on the inflamed mucosal site, supporting the recovery of a mutualistic community.
我们使用先前开发的体外模型来表征肠细胞粘附的微生物群部分，探讨了益生菌菌株动物双歧杆菌乳酸亚种BI07调节12名健康人类供体的肠细胞粘附微生物群炎症依赖性生态失调的潜力。根据我们的研究结果，动物双歧杆菌乳酸亚种BI07可有效限制炎症粘膜部位促炎致病共生菌的增加，支持互利共生群落的恢复。
