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通过酶封装提高基于过氧化氢酶的推进马达的耐久性。

Improving catalase-based propelled motor endurance by enzyme encapsulation.

机构信息

ICN2 - InstitutCatala de Nanociencia i Nanotecnologia, Campus UAB, 08193 Bellaterra (Barcelona), Spain CSIC Staff.

出版信息

Nanoscale. 2014 Aug 7;6(15):8907-13. doi: 10.1039/c4nr02459a.

Abstract

Biocatalytic propulsion is expected to play an important role in the future of micromotors as it might drastically increase the number of available fuelling reactions. However, most of the enzyme-propelled micromotors so far reported still rely on the degradation of peroxide by catalase, in spite of being vulnerable to relatively high peroxide concentrations. To overcome this limitation, herein we present a strategy to encapsulate the catalase and to graft the resulting enzyme capsules on motor particles. Significant improvement of the stability in the presence of peroxide and other aggressive agents has been observed.

摘要

生物催化推进有望在微马达的未来中发挥重要作用,因为它可能极大地增加可用的燃料反应数量。然而,迄今为止报道的大多数酶促微马达仍然依赖于过氧化氢酶对过氧化物的降解,尽管它们易受相对较高的过氧化物浓度的影响。为了克服这一限制,本文提出了一种封装过氧化氢酶并将所得酶胶囊接枝到马达颗粒上的策略。在存在过氧化物和其他刺激性试剂的情况下,稳定性得到了显著提高。

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