Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland.
Clin Infect Dis. 2014 Oct 15;59(8):e93-5. doi: 10.1093/cid/ciu487. Epub 2014 Jun 25.
Hypoglycemia was not previously known to be a linezolid-associated adverse reaction. A case report describing symptomatic hypoglycemia in a linezolid recipient prompted a review of the US Food and Drug Administration Adverse Event Reporting System, which demonstrated a relationship between linezolid and hypoglycemia. A warning with this information was added to the linezolid package insert.
低血糖以前并不被认为是利奈唑胺的不良反应。有一份病例报告描述了一名利奈唑胺使用者出现症状性低血糖，这促使美国食品和药物管理局不良事件报告系统对其进行了审查，结果显示利奈唑胺与低血糖之间存在关联。随后在利奈唑胺的药品说明书中添加了相关警示信息。
