Loprinzi Paul D, Abbott Kalen
Departments of Exercise Science and Physical Therapy, Donna & Allan Lansing School of Nursing & Health Sciences, Bellarmine University, Louisville, KY 40205, USA.
Maricopa Integrated Health System, Phoenix, AZ, USA.
J Diabetes Metab Disord. 2014 May 27;13:63. doi: 10.1186/2251-6581-13-63. eCollection 2014.
Although much is known about the management of peripheral arterial disease among adults in the general population, the management of this disease among those with diabetes, and the effects of diabetic-induced peripheral arterial disease on objectively-measured physical activity, is unclear. Here, we examined the association between accelerometer-assessed physical activity and peripheral arterial disease among a national sample of U.S. adults with diabetes.
Data from the 2003-2004 National Health and Nutrition Examination Survey were used. Physical activity was measured using an accelerometer in 254 adults with diabetes. Peripheral arterial disease was assessed via ankle brachial index. Negative binomial regression analysis was used to examine the association between physical activity and peripheral arterial disease.
Results were adjusted for age, gender, race-ethnicity, comorbidity index, smoking, HgbA1C, C-reactive protein, homocysteine, glomerular filtration rate, microalbuminuria, peripheral neuropathy, physical functioning, and medication use. After adjustments, participants with peripheral arterial disease engaged in 23% less physical activity (RR = 0.77, 95% CI: 0.62-0.96) than those without peripheral arterial disease.
These findings demonstrate an inverse association between accelerometer-assessed physical activity and peripheral arterial disease in a national sample of U.S adults with diabetes.
尽管对于普通人群中成年人外周动脉疾病的管理已有很多了解，但糖尿病患者中该疾病的管理以及糖尿病引发的外周动脉疾病对客观测量的身体活动的影响尚不清楚。在此，我们在美国成年糖尿病患者的全国样本中研究了加速度计评估的身体活动与外周动脉疾病之间的关联。
使用了2003 - 2004年国家健康和营养检查调查的数据。在254名成年糖尿病患者中使用加速度计测量身体活动。通过踝臂指数评估外周动脉疾病。采用负二项回归分析来研究身体活动与外周动脉疾病之间的关联。
对年龄、性别、种族、合并症指数、吸烟、糖化血红蛋白、C反应蛋白、同型半胱氨酸、肾小球滤过率、微量白蛋白尿、周围神经病变、身体功能和药物使用进行了结果调整。调整后，患有外周动脉疾病的参与者的身体活动比没有外周动脉疾病的参与者少23%（风险比 = 0.77，95%置信区间：0.62 - 0.96）。
这些发现表明，在美国成年糖尿病患者的全国样本中，加速度计评估的身体活动与外周动脉疾病之间存在负相关。
