Zhang Wu, Guo Fei, Wang Fei, Zhao Na, Liu Liang, Li Jia, Wang Zhenghua
Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials, College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, People's Republic of China.
Org Biomol Chem. 2014 Aug 14;12(30):5752-6. doi: 10.1039/c4ob00569d. Epub 2014 Jun 26.
CuO nanoparticles were found to be efficient catalysts for the synthesis of quinazoline derivatives; twenty-four products were obtained with good to excellent yields via reaction of N-arylamidines and aromatic aldehydes or benzyl alcohol in air. Neither a base nor an organic oxidant was necessary, and CuO nanoparticles can be recycled without a significant decrease in catalytic activity.
已发现氧化铜纳米颗粒是合成喹唑啉衍生物的有效催化剂；通过N-芳基脒与芳族醛或苄醇在空气中反应，以良好至优异的产率获得了24种产物。既不需要碱也不需要有机氧化剂，并且氧化铜纳米颗粒可以循环使用而催化活性不会显著降低。
