Ogembo Javier Gordon, Manga Simon, Nulah Kathleen, Foglabenchi Lily H, Perlman Stacey, Wamai Richard G, Welty Thomas, Welty Edith, Tih Pius
University of Massachusetts Medical School, Worcester, MA, United States.
Cameroon Baptist Convention Health Services, Bamenda, Cameroon.
Vaccine. 2014 Jul 31;32(35):4399-4403. doi: 10.1016/j.vaccine.2014.06.064. Epub 2014 Jun 24.
Cameroon has the highest age-standardized incidence rate of cervical cancer (30/100,000 women) in Central Africa. In 2010-2011, the Cameroon Baptist Convention Health Services (CBCHS) received donated human papillomavirus (HPV) vaccine, Gardasil, from Merck & Co. Inc. through Axios Healthcare Development to immunize 6400 girls aged 9-13 years. The aim was to inform the Cameroon Ministry of Health (MOH) of the acceptability, feasibility, and optimal delivery strategies for HPV vaccine.
Following approval by the MOH, CBCHS nurses educated girls, parents, and communities about HPV, cervical cancer, and HPV vaccine through multimedia coverage, brochures, posters, and presentations. Because educators were initially reluctant to allow immunization in schools, due to fear of adverse events, the nurses performed 40.7% of vaccinations in the clinics, 34.5% in community venues, and only 24.7% in schools. When no adverse events were reported, more schools and communities permitted HPV vaccine immunization on their premises. To recover administrative costs, CBCHS charged a fee of US$8 per 3-dose series only to those who were able to pay. Despite the fee, 84.6% of the 6,851 girls who received the first dose received all three doses.
With adequate education of all stakeholders, HPV vaccination is acceptable and feasible in Cameroon. Following this demonstration project, in 2014 the Global Access to Vaccines and Immunization (GAVI) Alliance awarded the Cameroon MOH HPV vaccine at a price of US$4.50 per dose to immunize sixth grade girls and girls aged 10 years who are not in school in two districts of Cameroon.
喀麦隆是中非宫颈癌年龄标准化发病率最高的国家（每10万名女性中有30例）。2010 - 2011年，喀麦隆浸信会健康服务组织（CBCHS）通过Axios Healthcare Development从默克公司获得了捐赠的人乳头瘤病毒（HPV）疫苗加德西，为6400名9至13岁的女孩进行免疫接种。目的是向喀麦隆卫生部通报HPV疫苗的可接受性、可行性和最佳接种策略。
在喀麦隆卫生部批准后，CBCHS的护士通过多媒体报道、宣传册、海报和演讲，向女孩、家长和社区宣传HPV、宫颈癌及HPV疫苗的相关知识。由于教育工作者最初因担心不良事件而不愿在学校进行免疫接种，护士在诊所进行了40.7%的疫苗接种，在社区场所进行了34.5%，而在学校仅进行了24.7%。当未报告不良事件时，更多学校和社区允许在其场所进行HPV疫苗接种。为收回行政成本，CBCHS仅向有支付能力的人收取每3剂系列8美元的费用。尽管收费，但接受首剂接种的6851名女孩中有84.6%接种了全部3剂。
通过对所有利益相关者进行充分教育，HPV疫苗接种在喀麦隆是可接受且可行的。在这个示范项目之后，2014年全球疫苗免疫联盟（GAVI）以每剂4.50美元的价格向喀麦隆卫生部提供HPV疫苗，为喀麦隆两个地区的六年级女孩和10岁未上学的女孩进行免疫接种。
