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小儿心脏导管插入术中患者体表入射剂量的直接测量。

Direct measurement of a patient's entrance skin dose during pediatric cardiac catheterization.

作者信息

Sun Lue, Mizuno Yusuke, Iwamoto Mari, Goto Takahisa, Koguchi Yasuhiro, Miyamoto Yuka, Tsuboi Koji, Chida Koichi, Moritake Takashi

机构信息

Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.

Department of Anesthesiology, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa 236-0004, Japan.

出版信息

J Radiat Res. 2014 Nov;55(6):1122-30. doi: 10.1093/jrr/rru050. Epub 2014 Jun 26.

Abstract

Children with complex congenital heart diseases often require repeated cardiac catheterization; however, children are more radiosensitive than adults. Therefore, radiation-induced carcinogenesis is an important consideration for children who undergo those procedures. We measured entrance skin doses (ESDs) using radio-photoluminescence dosimeter (RPLD) chips during cardiac catheterization for 15 pediatric patients (median age, 1.92 years; males, n = 9; females, n = 6) with cardiac diseases. Four RPLD chips were placed on the patient's posterior and right side of the chest. Correlations between maximum ESD and dose-area products (DAP), total number of frames, total fluoroscopic time, number of cine runs, cumulative dose at the interventional reference point (IRP), body weight, chest thickness, and height were analyzed. The maximum ESD was 80 ± 59 (mean ± standard deviation) mGy. Maximum ESD closely correlated with both DAP (r = 0.78) and cumulative dose at the IRP (r = 0.82). Maximum ESD for coiling and ballooning tended to be higher than that for ablation, balloon atrial septostomy, and diagnostic procedures. In conclusion, we directly measured ESD using RPLD chips and found that maximum ESD could be estimated in real-time using angiographic parameters, such as DAP and cumulative dose at the IRP. Children requiring repeated catheterizations would be exposed to high radiation levels throughout their lives, although treatment influences radiation dose. Therefore, the radiation dose associated with individual cardiac catheterizations should be analyzed, and the effects of radiation throughout the lives of such patients should be followed.

摘要

患有复杂先天性心脏病的儿童常常需要反复进行心导管检查;然而,儿童比成人对辐射更敏感。因此,对于接受这些检查的儿童来说,辐射诱发癌症是一个重要的考虑因素。我们使用放射光致发光剂量计(RPLD)芯片,在对15例患有心脏病的儿科患者(中位年龄1.92岁;男性9例,女性6例)进行心导管检查期间测量了皮肤入口剂量(ESD)。将四个RPLD芯片放置在患者胸部的后侧和右侧。分析了最大ESD与剂量面积乘积(DAP)、总帧数、总透视时间、电影拍摄次数、介入参考点(IRP)处的累积剂量、体重、胸部厚度和身高之间的相关性。最大ESD为80±59(平均值±标准差)mGy。最大ESD与DAP(r = 0.78)和IRP处的累积剂量(r = 0.82)密切相关。封堵术和球囊扩张术的最大ESD往往高于消融术、球囊房间隔造口术和诊断性操作。总之,我们使用RPLD芯片直接测量了ESD,并发现可以使用血管造影参数(如DAP和IRP处的累积剂量)实时估算最大ESD。尽管治疗会影响辐射剂量,但需要反复进行导管检查的儿童一生中会暴露于高辐射水平。因此,应分析与个体心导管检查相关的辐射剂量,并跟踪此类患者一生当中辐射的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f873/4229915/def8173d42cd/rru05001.jpg

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