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加拿大职业暴露致癌物评估扩展模型(CAREX Canada):一种评估职业致癌物暴露的增强模型

CAREX Canada: an enhanced model for assessing occupational carcinogen exposure.

作者信息

Peters Cheryl E, Ge Calvin B, Hall Amy L, Davies Hugh W, Demers Paul A

机构信息

School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada CAREX Canada, Simon Fraser University, Burnaby, British Columbia, Canada.

CAREX Canada, Simon Fraser University, Burnaby, British Columbia, Canada.

出版信息

Occup Environ Med. 2015 Jan;72(1):64-71. doi: 10.1136/oemed-2014-102286. Epub 2014 Jun 26.

Abstract

OBJECTIVES

To estimate the numbers of workers exposed to known and suspected occupational carcinogens in Canada, building on the methods of CARcinogen EXposure (CAREX) projects in the European Union (EU).

METHODS

CAREX Canada consists of estimates of the prevalence and level of exposure to occupational carcinogens. CAREX Canada includes occupational agents evaluated by the International Agency for Research on Cancer as known, probable or possible human carcinogens that were present and feasible to assess in Canadian workplaces. A Canadian Workplace Exposure Database was established to identify the potential for exposure in particular industries and occupations, and to create exposure level estimates among priority agents, where possible. CAREX EU data were reviewed for relevance to the Canadian context and the proportion of workers likely to be exposed by industry and occupation in Canada was assigned using expert assessment and agreement by a minimum of two occupational hygienists. These proportions were used to generate prevalence estimates by linkage with the Census of Population for 2006, and these estimates are available by industry, occupation, sex and province.

RESULTS

CAREX Canada estimated the number of workers exposed to 44 known, probable and suspected carcinogens. Estimates of levels of exposure were further developed for 18 priority agents. Common exposures included night shift work (1.9 million exposed), solar ultraviolet radiation exposure (1.5 million exposed) and diesel engine exhaust (781 000 exposed).

CONCLUSIONS

A substantial proportion of Canadian workers are exposed to known and suspected carcinogens at work.

摘要

目标

在欧盟致癌物暴露(CAREX)项目方法的基础上,估算加拿大接触已知和疑似职业致癌物的工人数量。

方法

加拿大CAREX项目包括对职业致癌物暴露患病率和暴露水平的估算。加拿大CAREX项目涵盖了国际癌症研究机构评估为已知、很可能或可能的人类致癌物的职业因素,这些因素在加拿大工作场所存在且可进行评估。建立了加拿大工作场所暴露数据库,以确定特定行业和职业中的暴露可能性,并在可能的情况下对重点因素进行暴露水平估算。对CAREX欧盟数据进行了审查,以确定其与加拿大情况的相关性,并通过专家评估和至少两名职业卫生学家的共识,确定加拿大按行业和职业划分的可能暴露工人比例。这些比例通过与2006年人口普查数据相联系,得出患病率估算值,这些估算值可按行业、职业、性别和省份获取。

结果

加拿大CAREX项目估算了接触44种已知、很可能和疑似致癌物的工人数量。还进一步得出了18种重点因素的暴露水平估算值。常见的暴露包括夜班工作(190万人暴露)、太阳紫外线辐射暴露(150万人暴露)和柴油机尾气暴露(78.1万人暴露)。

结论

相当一部分加拿大工人在工作中接触已知和疑似致癌物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e69/4283677/d0419698d1b9/oemed-2014-102286f01.jpg

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