Suppr超能文献

欧盟中职业性致癌物暴露情况

Occupational exposure to carcinogens in the European Union.

作者信息

Kauppinen T, Toikkanen J, Pedersen D, Young R, Ahrens W, Boffetta P, Hansen J, Kromhout H, Maqueda Blasco J, Mirabelli D, de la Orden-Rivera V, Pannett B, Plato N, Savela A, Vincent R, Kogevinas M

机构信息

Finnish Institute of Occupational Health, Helsinki, Finland.

出版信息

Occup Environ Med. 2000 Jan;57(1):10-8. doi: 10.1136/oem.57.1.10.

Abstract

OBJECTIVES

To construct a computer assisted information system for the estimation of the numbers of workers exposed to established and suspected human carcinogens in the member states of the European Union (EU).

METHODS

A database called CAREX (carcinogen exposure) was designed to provide selected exposure data and documented estimates of the number of workers exposed to carcinogens by country, carcinogen, and industry. CAREX includes data on agents evaluated by the International Agency for Research on Cancer (IARC) (all agents in groups 1 and 2A as of February 1995, and selected agents in group 2B) and on ionising radiation, displayed across the 55 industrial classes. The 1990-3 occupational exposure was estimated in two phases. Firstly, estimates were generated by the CAREX system on the basis of national labour force data and exposure prevalence estimates from two reference countries (Finland and the United States) which had the most comprehensive data available on exposures to these agents. For selected countries, these estimates were then refined by national experts in view of the perceived exposure patterns in their own countries compared with those of the reference countries.

RESULTS

About 32 million workers (23% of those employed) in the EU were exposed to agents covered by CAREX. At least 22 million workers were exposed to IARC group 1 carcinogens. The exposed workers had altogether 42 million exposures (1.3 mean exposures for each exposed worker). The most common exposures were solar radiation (9.1 million workers exposed at least 75% of working time), environmental tobacco smoke (7.5 million workers exposed at least 75% of working time), crystalline silica (3.2 million exposed), diesel exhaust (3.0 million), radon (2.7 million), and wood dust (2.6 million).

CONCLUSION

These preliminary estimates indicate that in the early 1990s, a substantial proportion of workers in the EU were exposed to carcinogens.

摘要

目标

构建一个计算机辅助信息系统,用于估算欧盟成员国中接触已确定和疑似人类致癌物的工人数量。

方法

设计了一个名为CAREX(致癌物暴露)的数据库,以提供选定的暴露数据,并按国家、致癌物和行业记录接触致癌物的工人数量估计值。CAREX包括国际癌症研究机构(IARC)评估的物质数据(截至1995年2月第1组和2A组的所有物质,以及2B组中的选定物质)和电离辐射数据,涵盖55个工业类别。1990 - 1993年的职业暴露分两个阶段进行估算。首先,CAREX系统根据国家劳动力数据和来自两个参考国家(芬兰和美国)的暴露患病率估计值生成估算值,这两个国家拥有关于这些物质暴露的最全面数据。对于选定的国家,然后由国家专家根据本国与参考国家相比的感知暴露模式对这些估算值进行完善。

结果

欧盟约3200万工人(占就业工人的23%)接触CAREX涵盖的物质。至少2200万工人接触IARC第1组致癌物。这些接触致癌物的工人总共经历了4200万次暴露(每位接触致癌物的工人平均1.3次暴露)。最常见的暴露包括太阳辐射(910万工人至少75%的工作时间暴露于此)、环境烟草烟雾(750万工人至少75%的工作时间暴露于此)、结晶二氧化硅(320万工人暴露)、柴油废气(300万工人暴露)、氡(270万工人暴露)和木尘(260万工人暴露)。

结论

这些初步估计表明,在20世纪90年代初,欧盟相当一部分工人接触致癌物。

相似文献

1
6
Occupational cancer in Britain. Exposure assessment methodology.英国职业癌。暴露评估方法学。
Br J Cancer. 2012 Jun 19;107 Suppl 1(Suppl 1):S18-26. doi: 10.1038/bjc.2012.114.
10
Estimating occupational exposure to carcinogens in Quebec.估算魁北克的职业性致癌物接触。
Am J Ind Med. 2013 Sep;56(9):1040-50. doi: 10.1002/ajim.22200. Epub 2013 Jun 26.

引用本文的文献

7
Silicosis: from pathogenesis to therapeutics.矽肺:从发病机制到治疗方法
Front Pharmacol. 2025 Jan 29;16:1516200. doi: 10.3389/fphar.2025.1516200. eCollection 2025.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验