Nakajima Kazunari, Kitagawa Mai, Ashida Yuya, Miyake Yoshihiro, Nishibayashi Yoshiaki
Institute of Engineering Innovation, School of Engineering, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo, 113-8656, Japan.
Chem Commun (Camb). 2014 Aug 18;50(64):8900-3. doi: 10.1039/c4cc03000a.
We have succeeded in the visible light-mediated synthetic use of α-aminoalkyl radicals derived from α-silyl secondary amines toward addition to α,β-unsaturated carbonyl compounds. The resulting γ-aminocarbonyl compounds are converted into γ-lactams and pyrroles in a one-pot process.
我们成功实现了在可见光介导下，将源自α-硅基仲胺的α-氨基烷基自由基用于加成到α,β-不饱和羰基化合物上。所得的γ-氨基羰基化合物可通过一锅法转化为γ-内酰胺和吡咯。
