a Department of Cognitive Neurology , Instituto de Investigaciones Neurológicas Raúl Carrea (FLENI) , Buenos Aires , Argentina.
Clin Neuropsychol. 2014;28(5):826-40. doi: 10.1080/13854046.2014.928748. Epub 2014 Jun 27.
Phototest is a simple, easy and very brief test with theoretical advantages over available dementia screening tests in Spain. The objective of this study was to estimate the diagnostic accuracy of the Phototest for cognitive impairment and dementia and to compare it with that of the MMSE and the Clock Drawing Test (CDT) in an Argentine population. A phase II cross-sectional study of diagnostic tests evaluation was performed in a sample of 30 controls, 61 with amnestic mild cognitive impairment (a-MCI), and 56 with mild Alzheimer type dementia (DAT). The diagnostic accuracy (DA) was assessed in relation to the clinical diagnosis by calculating the area under the ROC curve (UAC), Sensitivity (Sn), and Specificity (Sp).The DA of the Phototest for a-MCI and DAT (0.93 and 0.97 [UAC]) was higher than that of the MMSE and the CDT. The cut-off points of 27/28 for DAT (Sn = 89.29 [78.1-96.0], Sp = 96.67 [82.8-99.9]) and 30/31 for a-MCI (Sn = 85.25 [73.8-93.0], Sp = 90.00 [73.5-97.9]) maximized the sum of Sn and Sp. Phototest correlates significantly with MMSE and CDT. The Phototest is an efficient instrument for the detection of mild dementia or MCI, with good accuracy and good correlation with tests measuring overall cognitive impairment.
光测试是一种简单、易用且非常简短的测试，相对于西班牙现有的痴呆症筛查测试具有理论优势。本研究的目的是评估 Phototest 对认知障碍和痴呆的诊断准确性，并将其与 MMSE 和时钟绘图测试（CDT）在阿根廷人群中的准确性进行比较。一项横断面研究，评估了 30 名对照者、61 名遗忘型轻度认知障碍（a-MCI）患者和 56 名轻度阿尔茨海默病型痴呆（DAT）患者的诊断准确性。通过计算 ROC 曲线下面积（UAC）、敏感性（Sn）和特异性（Sp）来评估 Phototest 对临床诊断的诊断准确性（DA）。 Phototest 对 a-MCI 和 DAT 的 DA（0.93 和 0.97[UAC]）高于 MMSE 和 CDT。对于 DAT（Sn = 89.29 [78.1-96.0]，Sp = 96.67 [82.8-99.9]）和 a-MCI（Sn = 85.25 [73.8-93.0]，Sp = 90.00 [73.5-97.9]）的最佳截断点分别为 27/28 和 30/31，最大限度地提高了 Sn 和 Sp 的总和。 Phototest 与 MMSE 和 CDT 显著相关。 Phototest 是一种用于检测轻度痴呆或 MCI 的有效工具，具有良好的准确性和与全面认知障碍测试的良好相关性。
