Fineberg S K, Deutsch-Link S, Ichinose M, McGuinness T, Bessette A J, Chung C K, Corlett P R
S. K. Fineberg, MD, PhD, Yale University, Department of Psychiatry, Ribicoff Research Facility, New Haven, Connecticut; S. Deutsch-Link, BA, Yale University School of Medicine, New Haven, Connecticut; M. Ichinose, BA, T. McGuinness, BA, A. J. Bessette, BS, Yale University, Department of Psychiatry, New Haven, Connecticut; C. K. Chung, PhD, Department of Psychology, University of Texas at Austin, Austin, Texas; P. R. Corlett, PhD, Yale University, Department of Psychiatry, New Haven, Connecticut, USA.
Br J Psychiatry. 2015 Jan;206(1):32-8. doi: 10.1192/bjp.bp.113.140046. Epub 2014 Jun 26.
Language use is often disrupted in patients with schizophrenia; novel computational approaches may provide new insights.
To test word use patterns as markers of the perceptual, cognitive and social experiences characteristic of schizophrenia.
Word counting software was applied to first-person accounts of schizophrenia and mood disorder.
More third-person plural pronouns ('they') and fewer first-person singular pronouns ('I') were used in schizophrenia than mood disorder accounts. Schizophrenia accounts included fewer words related to the body and ingestion, and more related to religion. Perceptual and causal language were negatively correlated in schizophrenia accounts but positively correlated in mood disorder accounts.
Differences in pronouns suggest decreased self-focus or perhaps even an understanding of self as other in schizophrenia. Differences in how perceptual and causal words are correlated suggest that long-held delusions represent a decreased coupling of explanations with sensory experience over time.
精神分裂症患者的语言使用常常受到干扰;新颖的计算方法可能会提供新的见解。
测试词汇使用模式作为精神分裂症所特有的感知、认知和社会体验的标志物。
将词汇计数软件应用于精神分裂症和情绪障碍的第一人称叙述。
与情绪障碍叙述相比,精神分裂症叙述中使用的第三人称复数代词(“他们”)更多,第一人称单数代词(“我”)更少。精神分裂症叙述中与身体和摄入相关的词汇较少,与宗教相关的词汇较多。在精神分裂症叙述中,感知性语言和因果性语言呈负相关,而在情绪障碍叙述中呈正相关。
代词使用的差异表明精神分裂症患者自我关注减少,甚至可能将自我理解为他人。感知性词汇和因果性词汇相关性的差异表明,长期存在的妄想代表着随着时间推移,解释与感官体验之间的联系减少。