抗肿瘤蒽环类抗生素科斯莫霉素D的产生菌奥林登链霉菌DAUFPE 5622的基因组序列
Genome Sequence of Streptomyces olindensis DAUFPE 5622, Producer of the Antitumoral Anthracycline Cosmomycin D.
作者信息
Rojas Juan D, Starcevic Antonio, Baranas̆ić Damir, Ferreira-Torres Maria A, Contreras Camilo A, Garrido Leandro M, Araújo Welington L, de Souza Robson F, Zucko Jurica, Hranueli Daslav, Long Paul F, Cullum John, Padilla Gabriel
机构信息
Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Faculty of Food Technology and Biotechnology, University of Zagreb, Zagreb, Croatia.
出版信息
Genome Announc. 2014 Jun 26;2(3):e00541-14. doi: 10.1128/genomeA.00541-14.
Abstract
Streptomyces olindensis DAUFPE 5622, which was isolated from a Brazilian soil sample, produces the antitumor anthracycline cosmomycin D. The genome sequence is 9.4 Mb in length, with a G+C content of 71%. Thirty-four putative secondary metabolite biosynthetic gene clusters were identified, including the cosmomycin D cluster.
摘要
从巴西土壤样本中分离出的橄榄链霉菌DAUFPE 5622可产生抗肿瘤蒽环类抗生素科斯莫霉素D。其基因组序列长度为9.4 Mb，G+C含量为71%。已鉴定出34个推定的次生代谢物生物合成基因簇，包括科斯莫霉素D基因簇。
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