Angiuoli Samuel V, Gussman Aaron, Klimke William, Cochrane Guy, Field Dawn, Garrity George, Kodira Chinnappa D, Kyrpides Nikos, Madupu Ramana, Markowitz Victor, Tatusova Tatiana, Thomson Nick, White Owen
Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.
OMICS. 2008 Jun;12(2):137-41. doi: 10.1089/omi.2008.0017.
The methodologies used to generate genome and metagenome annotations are diverse and vary between groups and laboratories. Descriptions of the annotation process are helpful in interpreting genome annotation data. Some groups have produced Standard Operating Procedures (SOPs) that describe the annotation process, but standards are lacking for structure and content of these descriptions. In addition, there is no central repository to store and disseminate procedures and protocols for genome annotation. We highlight the importance of SOPs for genome annotation and endorse an online repository of SOPs.
用于生成基因组和宏基因组注释的方法多种多样，不同团队和实验室之间也存在差异。注释过程的描述有助于解读基因组注释数据。一些团队已经制定了描述注释过程的标准操作规程（SOP），但这些描述的结构和内容缺乏标准。此外，没有中央存储库来存储和传播基因组注释的程序和协议。我们强调了SOP对基因组注释的重要性，并支持建立一个SOP在线存储库。
