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子痫前期的高血压性脉络膜病变:两例连续病例。

Hypertensive choroidopathy in pre-eclampsia: two consecutive cases.

作者信息

Dewilde Evelien, Huygens Marc, Cools Geertrui, Van Calster Joachim

出版信息

Ophthalmic Surg Lasers Imaging Retina. 2014 Jul-Aug;45(4):343-6. doi: 10.3928/23258160-20140617-02. Epub 2014 Jun 30.

Abstract

Hypertensive retinopathy is well known, but choroidopathy is uncommon and associated with acute increases in blood pressure. Nonperfused areas of the choriocapillaris lead to changes of overlying retinal pigment epithelium (RPE), resulting in neurosensory or RPE detachments. The authors describe two patients with serous retinal detachments associated with acute arterial hypertension in pre-eclampsia and HELLP (hemolysis, elevated liver enzyme levels, and low platelet count) syndrome. Subretinal fluid was demonstrated on ultra-widefield fundus imaging and optical coherence tomography. Fluorescein angiography and indocyanine green angiography enabled imaging of the choroidal hypoperfusion. All signs and symptoms resolved after 1 and 3 months, respectively, with persistent macular pigmentary changes in both patients.

摘要

高血压性视网膜病变广为人知,但脉络膜病变并不常见,且与血压急性升高有关。脉络膜毛细血管无灌注区域会导致上方视网膜色素上皮(RPE)发生变化,进而引起神经感觉或RPE脱离。作者描述了两名患有浆液性视网膜脱离的患者,其与先兆子痫和HELLP(溶血、肝酶水平升高和血小板计数降低)综合征中的急性动脉高血压相关。超广角眼底成像和光学相干断层扫描显示了视网膜下液。荧光素血管造影和吲哚菁绿血管造影能够对脉络膜灌注不足进行成像。所有体征和症状分别在1个月和3个月后消失,两名患者均遗留持续性黄斑色素改变。

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