Jonas Jost B, Bourne Rupert R A, White Richard A, Flaxman Seth R, Keeffe Jill, Leasher Janet, Naidoo Kovin, Pesudovs Konrad, Price Holly, Wong Tien Y, Resnikoff Serge, Taylor Hugh R
Department of Ophthalmology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Vision and Eye Research Unit, Anglia Ruskin University, Cambridge, United Kingdom.
Am J Ophthalmol. 2014 Oct;158(4):808-15. doi: 10.1016/j.ajo.2014.06.012. Epub 2014 Jun 25.
To estimate the number of people visually impaired or blind due to macular diseases except those caused by diabetic maculopathy.
Meta-analysis.
Based on the Global Burden of Disease Study 2010 and ongoing literature research, we examined how many people were affected by vision impairment (presenting visual acuity <6/18, ≥3/60) and blindness (presenting visual acuity <3/60) due to macular diseases, with diabetic maculopathy excluded.
In 2010, of 32.4 million blind people and 191 million vision-impaired people, 2.1 million (95% uncertainty interval [UI]: 1.9, 2.7) people were blind, and 6.0 million (95% UI: 5.2, 8.1) million were visually impaired due to macular diseases. In 2010, macular diseases caused 6.6% (95% UI: 6.0, 7.9) of all blindness and 3.1% (95% UI: 2.7, 4.0) of all vision impairment, worldwide. These figures were lower in regions with young populations than in high-income regions. Between 1990 and 2010, the number of people who were blind or visually impaired due to macular diseases increased by 36%, or 0.6 million people (95% UI: 0.5, 0.8) and by 81%, or 2.7 million (95% UI: 2.6, 3.9) people, respectively, whereas the global population increased by 30%. Age-standardized global prevalence of macula-related blindness and vision impairment in adults 50 years of age and older decreased from 0.2% (95% UI: 0.2, 0.2) in 1990 to 0.1% (95% UI: 0.1, 0.2) in 2010 and remained unchanged from 0.4% (95% UI: 0.3, 0.5) to 0.4% (95% UI: 0.4, 0.6), respectively.
In 2010, 2.1 million people were blind and 6.0 million people were visually impaired due to macular diseases, except those caused by diabetic maculopathy. Of every 15 blind people, 1 was blind due to macular disease, and of every 32 visually impaired people, 1 was visually impaired due to macular disease.
估算除糖尿病性黄斑病变外，因黄斑疾病导致视力受损或失明的人数。
荟萃分析。
基于《2010年全球疾病负担研究》及持续的文献研究，我们调查了有多少人因黄斑疾病（不包括糖尿病性黄斑病变）而出现视力损害（视力<6/18，≥3/60）和失明（视力<3/60）。
2010年，在3240万盲人及1.91亿视力受损者中，有210万（95%不确定区间[UI]：190万，270万）人因黄斑疾病而失明，600万（95% UI：520万，810万）人因黄斑疾病而视力受损。2010年，黄斑疾病导致全球所有失明病例中的6.6%（95% UI：6.0%，7.9%）以及所有视力损害病例中的3.1%（95% UI：2.7%，4.0%）。在年轻人口较多的地区，这些数字低于高收入地区。1990年至2010年期间，因黄斑疾病而失明或视力受损的人数分别增加了36%，即60万人（95% UI：50万，80万）和81%，即270万人（95% UI：260万，390万），而全球人口增加了30%。50岁及以上成年人中，与黄斑相关的失明和视力损害的年龄标准化全球患病率从1990年的0.2%（95% UI：0.2%，0.2%）降至2010年的0.1%（95% UI：0.1%，0.2%），分别保持在0.4%（95% UI：0.3%，0.5%）至0.4%（95% UI：0.4%，0.6%）不变。
2010年，除糖尿病性黄斑病变外，有210万人因黄斑疾病而失明，600万人因黄斑疾病而视力受损。每15名盲人中就有1人因黄斑疾病失明，每32名视力受损者中就有1人因黄斑疾病视力受损。
