Yajima Katsuhiko, Seya Tomomi, Iwayama Kaito, Hibi Masanobu, Hari Sayaka, Nakashima Yu, Ogata Hitomi, Omi Naomi, Satoh Makoto, Tokuyama Kumpei
Department of Administrative Nutrition, Faculty of Health and Nutrition, Tokyo Seiei College.
J Nutr Sci Vitaminol (Tokyo). 2014;60(2):114-21. doi: 10.3177/jnsv.60.114.
Energy metabolism and substrate oxidation during sleep correlate with sleep stage, suggesting that energy metabolism affects sleep architecture or vice versa. The aim of the present study was to examine whether changes in energy metabolism during sleep, induced by a high-carbohydrate or high-fat meal for dinner, affect sleep architecture. Ten healthy males participated in this study, sleeping 3 nonconsecutive nights in a whole-room calorimeter. The first night was scheduled as an adaptation to the experimental environment. The other 2 nights were experimental calorimetry in a balanced cross-over design with intrasubject comparisons. In each session, subjects comsumed a high carbohydrate (HCD: PFC=10 : 10 : 80) or high fat (HFD: PFC=10 : 78 : 12) meal at 2000 h and slept with a polysomnographic recording in a metabolic chamber for indirect calorimetry (0000 h to 0800 h). Slow wave sleep was decreased during the first sleep cycle and not changed during the second or third sleep cycle under HCD conditions compared with those of HFD. Energy expenditure was not affected by dietary condition but substrate oxidation reflected differences in dietary composition of the dinner during the first and second sleep cycle. The present study suggested the possibility that substrate availability during sleep affects substrate oxidation during sleep, and affects sleep architecture during the first sleep cycle.
睡眠期间的能量代谢和底物氧化与睡眠阶段相关，这表明能量代谢会影响睡眠结构，反之亦然。本研究的目的是检验晚餐摄入高碳水化合物或高脂肪食物所引起的睡眠期间能量代谢变化是否会影响睡眠结构。十名健康男性参与了本研究，他们在全室热量计中连续三个晚上不连续睡眠。第一个晚上安排用于适应实验环境。另外两个晚上采用平衡交叉设计进行实验性热量测定，并进行受试者内比较。在每个时间段，受试者于20:00摄入高碳水化合物餐（HCD：PFC = 10 : 10 : 80）或高脂肪餐（HFD：PFC = 10 : 78 : 12），并在代谢室中进行多导睡眠图记录以进行间接热量测定（0:00至8:00）。与高脂肪餐相比，在高碳水化合物餐条件下，慢波睡眠在第一个睡眠周期减少，在第二个或第三个睡眠周期未发生变化。能量消耗不受饮食条件影响，但底物氧化反映了晚餐饮食组成在第一个和第二个睡眠周期的差异。本研究表明，睡眠期间的底物可用性可能会影响睡眠期间的底物氧化，并在第一个睡眠周期影响睡眠结构。
