Séguin Jean R
Université de Montréal, Montréal, Québec, and Centre de Recherche Centre Hospitalier Universitaire Ste-Justine, Montréal, Québec, Canada.
Eur J Dev Psychol. 2009 Jan 5;6(1):100-119. doi: 10.1080/17405620701669871.
Frontal lesions often lead to psychosocial problems. It is not surprising that frontal lobe dysfunctions have been proposed to underlie antisocial behaviour in individuals without apparent lesions. However, physical aggression and violence have never been systematically related to acquired lesions. Whereas, traditional neuropsychological testing identifies problems in cognitive and emotional information processing, recent brain-imaging studies have revealed both the frontal structural and functional underpinnings of antisocial behaviour. Careful characterization of antisocial behaviour subtypes seems to indicate that cognitive-neuropsychological function is systematically poor in physical aggression and hyperactivity. Recent refinements point to biological and genetic moderators of that association.
额叶病变常常导致心理社会问题。毫不奇怪，有人提出额叶功能障碍是无明显病变个体反社会行为的潜在原因。然而，身体攻击和暴力行为从未与后天性病变有过系统的关联。传统的神经心理学测试能够识别认知和情感信息处理方面的问题，而最近的脑成像研究揭示了反社会行为的额叶结构和功能基础。对反社会行为亚型的仔细刻画似乎表明，在身体攻击和多动方面，认知神经心理功能系统性地较差。最近的研究进展指出了这种关联的生物学和遗传调节因素。
