Azarisman Shah M, Teo Karen S, Worthley Matthew I, Worthley Stephen G
Shah M Azarisman, Department of Internal Medicine, Kulliyyah of Medicine, International Islamic University Malaysia, Bandar InderaMahkota, 25200 Kuantan, Pahang, Malaysia.
World J Cardiol. 2014 Jun 26;6(6):405-14. doi: 10.4330/wjc.v6.i6.405.
Cardiovascular disease (CVD) is the leading cause of death in the western world and is becoming more important in the developing world. Recently, advances in monitoring, revascularisation and pharmacotherapy have resulted in a reduction in mortality. However, although mortality rates have declined, the burden of disease remains large resulting in high direct and indirect healthcare costs related to CVDs. In Australia, acute coronary syndrome (ACS) accounts for more than 300000 years of life lost due to premature death and a total cost exceeding eight billion dollars annually. It is also the main contributor towards the discrepancy in life expectancy between indigenous and non-indigenous Australians. The high prevalence of CVD along with its associated cost urgently requires a reliable but non-invasive and cost-effective imaging modality. The imaging modality of choice should be able to accelerate the diagnosis of ACS, aid in the risk stratification of de novo coronary artery disease and avail incremental information of prognostic value such as viability which cardiovascular magnetic resonance (CMR) allows. Despite its manifold benefits, there are limitations to its wider use in routine clinical assessment and more studies are required into assessing its cost-effectiveness. It is hoped that with greater development in the technology and imaging protocols, CMR could be made less cumbersome, its imaging protocols less lengthy, the technology more inexpensive and easily applied in routine clinical practice.
心血管疾病(CVD)是西方世界的主要死因,在发展中世界也日益重要。最近,监测、血管重建和药物治疗方面的进展已使死亡率有所降低。然而,尽管死亡率有所下降,但疾病负担仍然很大,导致与心血管疾病相关的直接和间接医疗费用高昂。在澳大利亚,急性冠状动脉综合征(ACS)导致超过30万年的潜在寿命损失,每年的总成本超过80亿美元。它也是导致澳大利亚原住民和非原住民预期寿命差异的主要因素。心血管疾病的高患病率及其相关成本迫切需要一种可靠、无创且具有成本效益的成像方式。首选的成像方式应能够加速急性冠状动脉综合征的诊断,有助于对新发冠状动脉疾病进行风险分层,并提供具有预后价值的增量信息,如心肌存活性,而心血管磁共振(CMR)就能做到这一点。尽管它有诸多益处,但在常规临床评估中更广泛使用仍存在局限性,需要更多研究来评估其成本效益。希望随着技术和成像方案的进一步发展,心血管磁共振能够变得不那么繁琐,成像方案不那么冗长,技术成本更低且易于应用于常规临床实践中。