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多尺度功能与分子光声断层成像

Multiscale Functional and Molecular Photoacoustic Tomography.

作者信息

Yao Junjie, Xia Jun, Wang Lihong V

机构信息

Optical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St. Louis, MO, USA.

Optical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St. Louis, MO, USA Department of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY, USA.

出版信息

Ultrason Imaging. 2016 Jan;38(1):44-62. doi: 10.1177/0161734615584312. Epub 2015 May 1.

DOI:10.1177/0161734615584312
PMID:25933617
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4628905/
Abstract

Photoacoustic tomography (PAT) combines rich optical absorption contrast with the high spatial resolution of ultrasound at depths in tissue. The high scalability of PAT has enabled anatomical imaging of biological structures ranging from organelles to organs. The inherent functional and molecular imaging capabilities of PAT have further allowed it to measure important physiological parameters and track critical cellular activities. Integration of PAT with other imaging technologies provides complementary capabilities and can potentially accelerate the clinical translation of PAT.

摘要

光声断层扫描(PAT)将丰富的光学吸收对比度与组织深部超声的高空间分辨率相结合。PAT的高可扩展性使得从细胞器到器官等生物结构的解剖成像成为可能。PAT固有的功能和分子成像能力进一步使其能够测量重要的生理参数并追踪关键的细胞活动。将PAT与其他成像技术相结合可提供互补功能,并有可能加速PAT的临床转化。

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