Wada Tomoyuki, Anai Hirofumi, Shuto Takashi, Okamoto Keitaro, Kawano Madoka, Kozaki Satoshi, Hirota Jun, Miyamoto Shinji
Department of Cardiovascular Surgery, Oita University Hospital, 1-1-1 Idai-ga-oka, Hazama, Yufu, Oita, 879-5593, Japan.
Gen Thorac Cardiovasc Surg. 2016 Apr;64(4):227-30. doi: 10.1007/s11748-014-0440-8. Epub 2014 Jul 1.
A 54-year-old woman initially diagnosed with stage IIIb squamous cell carcinoma of the uterine cervix was treated with chemotherapy and radiation therapy. After 8 months, she developed dyspnea, leg edema, pleural effusion, pericardial effusion, and liver congestion. Her cardiac ejection fraction was normal and cardiomegaly was not evident. Metastatic carcinomatous pericarditis or pleurisy was suspected, but laboratory findings, including tumor markers, were normal. She was transferred to our hospital for the repair a cardiac injury caused by a pericardial drainage procedure. Emergency surgery was performed for the misplaced drainage catheter in the right atrium and for an abnormal mass in her right and left atria. The clinical diagnosis of carcinomatous pericarditis was made; however, her condition rapidly deteriorated, and she died 6 days postoperatively. At autopsy, metastasis was identified in a large area of the pericardium and myocardium.
一名54岁女性最初被诊断为IIIb期子宫颈鳞状细胞癌，接受了化疗和放射治疗。8个月后，她出现呼吸困难、腿部水肿、胸腔积液、心包积液和肝脏充血。她的心脏射血分数正常，未发现心脏扩大。怀疑为转移性癌性心包炎或胸膜炎，但包括肿瘤标志物在内的实验室检查结果均正常。她因心包引流术导致的心脏损伤修复被转至我院。因右心房引流导管位置不当以及左右心房出现异常肿块而进行了急诊手术。临床诊断为癌性心包炎；然而，她的病情迅速恶化，术后6天死亡。尸检发现心包和心肌大面积转移。
