Chen Shuai, Chen Lili, Chen Kaixian, Shen Xu, Jiang Hualiang
Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.
Drug Discov Today Technol. 2006 Autumn;3(3):277-83. doi: 10.1016/j.ddtec.2006.09.005.
Severe acute respiratory syndrome coronavirus (SARS-CoV) is the etiological agent of SARS disease, which has ever severely menaced humans from the end of 2002 to June 2003. To date, great efforts have been made for the discovery of therapeutic compounds by using various technologies. In this report, we present a survey of these techniques and their applications in the development of promising anti-SARS agents.:
严重急性呼吸综合征冠状病毒(SARS-CoV)是SARS疾病的病原体,在2002年底至2003年6月期间曾严重威胁人类。迄今为止,人们已经通过各种技术大力寻找治疗性化合物。在本报告中,我们对这些技术及其在开发有前景的抗SARS药物中的应用进行了综述。