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首次发作后右半结肠单纯性憩室炎复发的危险因素。

Risk factors for recurrence of right colonic uncomplicated diverticulitis after first attack.

作者信息

Park Hyoung-Chul, Kim Byung Seup, Lee Kwanseop, Kim Min Jeong, Lee Bong Hwa

机构信息

Department of Surgery, Hallym University College of Medicine, 896 Pyeongchon-dong, Dongan-gu, Anyang, 431-070, Republic of Korea.

出版信息

Int J Colorectal Dis. 2014 Oct;29(10):1217-22. doi: 10.1007/s00384-014-1941-8. Epub 2014 Jul 1.

DOI:10.1007/s00384-014-1941-8
PMID:24980689
Abstract

PURPOSE

Most patients with acute right colonic uncomplicated diverticulitis can be managed conservatively. The aim of this study was to assess the clinical and radiologic risk factors for recurrence in patients with right colonic uncomplicated diverticulitis.

METHODS

The present survey included 469 patients who were successfully managed conservatively for the first episode of right colonic uncomplicated diverticulitis between 2002 and 2012 in a referral center, and records were reviewed from collected data. Patients were divided into two groups: a nonrecurrent and a recurrent group. The clinical and radiologic features of all patients were analyzed to identify possible risk factors for recurrence. The Kaplan-Meier method and Cox regression were used.

RESULTS

Seventy-four (15.8 %) patients had recurrence, and 15 (3.2 %) received surgery at recurrence within a median follow-up of 59 months. The mean recurrence interval after the first attack was 29 months. In univariate and multivariate analyses, risk factors for recurrence were confirmed multiple diverticula (relative risk [RR], 2.62; 95 % confidence interval [CI], 1.56-4.40) and intraperitoneally located diverticulitis (RR, 3.73; 95 % CI, 2.13-6.52). Of 66 patients with two risk factors, 36 (54.5 %) had recurrence and 10 (15.2 %) received surgery at recurrence.

CONCLUSIONS

In patients with right colonic uncomplicated diverticulitis who have multiple diverticula and intraperitoneally located diverticulitis, the possibility of recurrence and surgical rate are high. Poor outcome may be cautioned in these patients.

摘要

目的

大多数急性右半结肠非复杂性憩室炎患者可采用保守治疗。本研究旨在评估右半结肠非复杂性憩室炎患者复发的临床和影像学危险因素。

方法

本调查纳入了2002年至2012年间在一家转诊中心首次因右半结肠非复杂性憩室炎成功接受保守治疗的469例患者,并对收集的数据记录进行了回顾。患者分为两组:非复发组和复发组。分析所有患者的临床和影像学特征,以确定可能的复发危险因素。采用Kaplan-Meier法和Cox回归分析。

结果

74例(15.8%)患者复发,15例(3.2%)在复发时接受了手术,中位随访时间为59个月。首次发作后的平均复发间隔为29个月。单因素和多因素分析显示,复发的危险因素为多发憩室(相对危险度[RR],2.62;95%可信区间[CI],1.56 - 4.40)和腹膜内憩室炎(RR,3.73;95%CI,2.13 - 6.52)。在66例有两个危险因素的患者中,36例(54.5%)复发,10例(15.2%)在复发时接受了手术。

结论

在患有多发憩室和腹膜内憩室炎的右半结肠非复杂性憩室炎患者中,复发可能性和手术率较高。对这些患者可能要警惕不良预后。

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