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抗阻运动后血流动力学和自主神经反应:正常血压男性与高血压男性的比较。

Post-resistance exercise hemodynamic and autonomic responses: Comparison between normotensive and hypertensive men.

作者信息

Queiroz A C C, Sousa J C S, Cavalli A A P, Silva N D, Costa L A R, Tobaldini E, Montano N, Silva G V, Ortega K, Mion D, Tinucci T, Forjaz C L M

机构信息

Exercise Hemodynamic Laboratory, School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil.

Department of Biomedical and Clinical Sciences "L. Sacco", Medicine and Physiopathology, L. Sacco Hospital, University of Milan, Milan, Italy.

出版信息

Scand J Med Sci Sports. 2015 Aug;25(4):486-94. doi: 10.1111/sms.12280. Epub 2014 Jul 1.

Abstract

To compare post-resistance exercise hypotension (PREH) and its mechanisms in normotensive and hypertensive individuals, 14 normotensives and 12 hypertensives underwent two experimental sessions: control (rest) and exercise (seven exercises, three sets, 50% of one repetition maximum). Hemodynamic and autonomic clinic measurements were taken before (Pre) and at two moments post-interventions (Post 1: between 30 and 60 min; Post 2: after 7 h). Ambulatory blood pressure (BP) was monitored for 24 h. At Post 1, exercise decreased systolic BP similarly in normotensives and hypertensives (-8 ± 2 vs -13 ± 2 mmHg, P > 0.05), whereas diastolic BP decreased more in hypertensives (-4 ± 1 vs -9 ± 1 mmHg, P < 0.05). Cardiac output and systemic vascular resistance did not change in normotensives and hypertensives (0.0 ± 0.3 vs 0.0 ± 0.3 L/min; -1 ± 1 vs -2 ± 2 U, P > 0.05). After exercise, heart rate (+13 ± 3 vs +13 ± 2 bpm) and its variability (low- to high-frequency components ratio, 1.9 ± 0.4 vs +1.4 ± 0.3) increased whereas stroke volume (-14 ± 5 vs -11 ± 5 mL) decreased similarly in normotensives and hypertensives (all, P > 0.05). At Post 2, all variables returned to pre-intervention, and ambulatory data were similar between sessions. Thus, a session of resistance exercise promoted PREH in normotensives and hypertensives. Although this PREH was greater in hypertensives, it did not last during the ambulatory period, which limits its clinical relevance. In addition, the mechanisms of PREH were similar in hypertensives and normotensives.

摘要

为比较血压正常者和高血压患者运动后低血压(PREH)及其机制,14名血压正常者和12名高血压患者进行了两个实验阶段:对照(休息)和运动(七项运动,三组,每组重复最大值的50%)。在干预前(Pre)以及干预后两个时刻(Post 1:30至60分钟之间;Post 2:7小时后)进行血流动力学和自主神经临床测量。监测24小时动态血压(BP)。在Post 1时,血压正常者和高血压患者运动后收缩压下降程度相似(-8±2 vs -13±2 mmHg,P>0.05),而高血压患者舒张压下降幅度更大(-4±1 vs -9±1 mmHg,P<0.05)。血压正常者和高血压患者的心输出量和全身血管阻力无变化(0.0±0.3 vs 0.0±0.3 L/min;-1±1 vs -2±2 U,P>0.05)。运动后,血压正常者和高血压患者的心率(+13±3 vs +13±2 bpm)及其变异性(低频与高频成分比值,1.9±0.4 vs +1.4±0.3)增加,而每搏输出量下降程度相似(-14±5 vs -11±5 mL)(均为P>0.05)。在Post 2时,所有变量均恢复至干预前水平,且各阶段的动态数据相似。因此,一次抗阻运动可促使血压正常者和高血压患者出现运动后低血压。尽管高血压患者的这种运动后低血压更为明显,但在动态监测期间并未持续存在,这限制了其临床相关性。此外,高血压患者和血压正常者运动后低血压的机制相似。

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