Maruf Fatai A, Salako Babatunde L, Akinpelu Aderonke O
aDepartment of Medical Rehabilitation, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Nnewi Campus, Nnewi bDepartment of Medicine, Nephrology Unit cDepartment of Physiotherapy, Faculty of Clinical Sciences, University of Ibadan, Ibadan, Nigeria.
J Cardiovasc Med (Hagerstown). 2014 Jun;15(6):456-62. doi: 10.2459/JCM.0b013e32836263b2.
Achieving adequate blood pressure (BP) control with antihypertensive medication remains an elusive goal for many patients. The advances in knowledge of hypertension and the increasingly improved upon therapeutic strategies seem not to guarantee even sustainable control rates at the population level. In addition, patients who either discontinue their medications or are non-adherent to drug therapy run the risk of developing uncontrolled BP. Number of daily tablets more than two and number of daily drug administration at least three have been associated with poor adherence with drug therapy. However, BP control seems to go beyond adherence with drug therapy as there are other associated factors. Studies have demonstrated beneficial effect of aerobic exercise in the prevention and management of hypertension. It appears, however, that the majority of these studies failed to explore the possible additive or synergistic effect of aerobic exercise on antihypertensive drugs such that fewer drugs would be required to achieve BP control or that the BP control rate would be increased with the same number of drugs. This review presents the evidence for poor BP control in the general population, and the possible means and process of aerobic exercise complementing antihypertensive drug therapy in order to achieve higher BP control rates.
对许多患者而言，通过抗高血压药物实现充足的血压控制仍是一个难以实现的目标。高血压知识的进步以及治疗策略的日益改进似乎并未保证在人群层面达到可持续的控制率。此外，停止用药或不坚持药物治疗的患者有血压失控的风险。每日服用片剂数量超过两片以及每日至少服药三次与药物治疗依从性差有关。然而，血压控制似乎不仅仅取决于药物治疗的依从性，还存在其他相关因素。研究表明有氧运动在高血压的预防和管理中具有有益作用。然而，这些研究中的大多数似乎未能探索有氧运动对降压药物可能产生的相加或协同作用，即实现血压控制所需药物更少，或者使用相同数量的药物可提高血压控制率。本综述阐述了普通人群中血压控制不佳的证据，以及有氧运动补充降压药物治疗以实现更高血压控制率的可能方法和过程。
