响应性和“智能”抗菌表面：常见方法与新进展（综述）

Responsive and "smart" antibacterial surfaces: common approaches and new developments (Review).

作者信息

Cavallaro Alex, Taheri Shima, Vasilev Krasimir

机构信息

School of Engineering, University of South Australia, Mawson Lakes, South Australia 5095, Australia.

School of Engineering, University of South Australia, Mawson Lakes, South Australia 5095, Australia and Mawson Institute, University of South Australia, Mawson Lakes, South Australia 5095, Australia.

出版信息

Biointerphases. 2014 Jun;9(2):029005. doi: 10.1116/1.4866697.

DOI:10.1116/1.4866697

PMID:24985209

Abstract

Bacterial infections are continuing to pose a significant threat to human health. Coatings with inherent antibacterial properties are becoming increasingly common as an infection preventative measure. The aim of this review is to highlight recent progress in development of "smart" and responsive antibacterial surfaces. The review describes various strategies utilized for generation of such surfaces and the specific stimuli that are used to trigger antibacterial action. It also provides a critical discussion of the advantages and drawbacks of different approaches. The review concludes with a perspective about the future of the field and outlines the challenges and obstacles that need to be overcome in order to make future advances.

摘要

细菌感染持续对人类健康构成重大威胁。具有固有抗菌特性的涂层作为一种感染预防措施正变得越来越普遍。本综述的目的是突出“智能”和响应性抗菌表面开发的最新进展。该综述描述了用于生成此类表面的各种策略以及用于触发抗菌作用的特定刺激因素。它还对不同方法的优缺点进行了批判性讨论。综述最后展望了该领域的未来，并概述了为取得未来进展需要克服的挑战和障碍。