[中国浙江省2005 - 2010年乳腺癌、宫颈癌和卵巢癌患者生存率分析]

[Analysis of survival rate of breast, cervical, and ovarian cancer patients during 2005-2010 in Zhejiang province, China].

作者信息

Gong Weiwei, Luo Shenglan, Hu Ruying, Wang Hao, Pan Jin, Fei Fangrong, He Qingfang, Yu Min

机构信息

Department of Non-Communicable Disease Control, Zhejiang Provincial Centre for Disease Control and Prevention, Hangzhou 310051, China.

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出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 2014 May;48(5):366-9.

PMID:24985374

Abstract

OBJECTIVE

To provide reference information for prognosis and control of female cancers by analyzing survival rates of breast, cervical and ovarian cancer patients during 2005-2010 in Zhejiang province.

METHODS

The morbidity and mortality data of 18 133 breast, cervical and ovarian cancer patients whose information were registered in health surveillance zone during 2005-2010 in Zhejiang were analyzed. The December 31(st), 2012 was set as the deadline of survival time. Observed survival rate (OS) and relative survival rate (RS) were calculated using SURV3.01 software and comparison between survival rates was conducted through Hakulinen's likely hood ratio test.

RESULTS

The 5-year OS of breast cancer, cervical cancer, and ovarian cancer were 76.89%, 70.79%, 2.59%, respectively during 2005-2010 in Zhejiang province. The 5-year RS of the three cancers were 80.26%, 73.89%, 55.17%, respectively. The 5-year RS of breast cancer, cervical cancer, and ovarian cancer in urban area were 83.11%, 77.87%, and 57.22% and 78.00%, 72.21%, and 53.83% in rural areas, respectively. The overall RS of urban patients was higher than the rural's (χ(2) = 24.98, 11.55 and 6.62, respectively, all P values < 0.05). The 5-year RS of breast cancer, which was grouped by age, showed that the 15-44 years group was the highest (83.40%), while 65-77 years group was the lowest (74.67%). The 5-year RS of cervical cancer decreased with age, with a 41.73% decrease from 83.83% (15-44 years group) to 42.10% ( ≥ 75 years group). The 15-44 years group showed the highest 5-year RS of ovarian cancer (74.30%), while ≥ 75 years group was the lowest (41.80%).

CONCLUSION

The prognosis of breast cancer and cervical cancer were relatively optimistic, while the ovarian cancer was not. The prognosis of female cancer patients in urban areas were better than in rural areas.

摘要

目的

通过分析2005 - 2010年浙江省乳腺癌、宫颈癌和卵巢癌患者的生存率，为女性癌症的预后和控制提供参考信息。

方法

对2005 - 2010年浙江省健康监测区登记的18133例乳腺癌、宫颈癌和卵巢癌患者的发病和死亡数据进行分析。将2012年12月31日设定为生存时间的截止日期。使用SURV3.01软件计算观察生存率（OS）和相对生存率（RS），并通过Hakulinen似然比检验进行生存率比较。

结果

2005 - 2010年浙江省乳腺癌、宫颈癌和卵巢癌的5年OS分别为76.89%、70.79%、2.59%。三种癌症的5年RS分别为80.26%、73.89%、55.17%。城市地区乳腺癌、宫颈癌和卵巢癌的5年RS分别为83.11%、77.87%和57.22%，农村地区分别为78.00%、72.21%和53.83%。城市患者的总体RS高于农村患者（χ(2)分别为24.98、11.55和6.62，所有P值<0.05）。按年龄分组的乳腺癌5年RS显示，15 - 44岁组最高（83.40%），而65 - 77岁组最低（74.67%）。宫颈癌的5年RS随年龄下降，从83.83%（15 - 44岁组）降至42.10%（≥75岁组），下降了41.73%。15 - 44岁组卵巢癌的5年RS最高（74.30%），而≥75岁组最低（41.80%）。