Zalke Ashish S, Duraiswamy B, Gandagule Upendra B
Department of Pharmacognosy, JSS College of Pharmacy, Rocklands, Ooty, Tamil Nadu, India.
Anc Sci Life. 2013 Apr;32(4):187-92. doi: 10.4103/0257-7941.131969.
Combretum albidum Don belonging to family Combretaceae is an unexplored medicinal plant in the Indian medicinal system. According to ethnobotanical information, the leaves are used in the treatment of peptic ulcer and its fruits are used in diarrhoea and dysentery. Stem bark is used in the treatment of jaundice and skin diseases. The problem encountered in standardisation of this medicinal plant is its identification by source.
The pharmacognostical studies were carried out in terms of organoleptic, macroscopic, microscopic, physicochemical, florescence and phytochemical analysis. Physicochemical parameters such as total ash, moisture content and extractive values are determined by World Health Organization guidelines. The microscopic features of leaf components are observed with Nikon lab photo device with microscopic units.
Macroscopically, the leaves are simple, obovate in shape, acuminate apex, entire margin and smooth surface. Microscopically, the leaves showed a large vascular strand that consists of thick walled xylem elements mixed with xylem fibres and phloem which is present in a thin layer along inner and outer portions of xylem. External to the xylem occur a thin line of sclerenchyma. Powder microscopy revealed glandular trichomes in the adaxial epidermal peelings also shows the non-glandular trichomes fairly common in powder and epidermis with anisocytic stomata. Vessels elements are narrow, long, cylindrical and dense multi-seriate bordered pits. Xylem fibres are thin and long, with thick walls, which are lignified. Preliminary phytochemical screening showed the presence of carbohydrate, glycoside, saponin, flavonoid, phytosterols and phenolic compounds.
The results of the study can serve as a valuable source of pharmacognostic information as suitable standards for identification of this plant material in future investigations and applications.
白花风车子(Combretum albidum Don)属于使君子科,是印度药用体系中一种尚未被充分研究的药用植物。根据民族植物学信息,其叶用于治疗消化性溃疡,果实用于治疗腹泻和痢疾。茎皮用于治疗黄疸和皮肤病。这种药用植物标准化过程中遇到的问题是其来源鉴定。
进行了感官、宏观、微观、理化、荧光和植物化学分析等生药学研究。按照世界卫生组织的指导方针测定总灰分、水分含量和浸出物值等理化参数。使用配备显微镜单元的尼康实验室摄影设备观察叶片成分的微观特征。
宏观上,叶片为单叶,倒卵形,先端渐尖,边缘全缘,表面光滑。微观上,叶片显示出一条大的维管束,由厚壁木质部成分与木质纤维和韧皮部混合而成,韧皮部沿木质部的内部和外部呈薄层存在。木质部外部有一条薄壁组织细线。粉末显微镜检查显示,近轴表皮剥片中有腺毛,粉末和表皮中也相当常见非腺毛,气孔为不等细胞型。导管分子狭窄、细长、圆柱形,具密集的多列具缘纹孔。木质纤维细而长,壁厚,木质化。初步植物化学筛选表明存在碳水化合物、糖苷、皂苷、黄酮类、植物甾醇和酚类化合物。
该研究结果可作为有价值的生药学信息来源,为未来该植物材料的鉴定提供合适标准,以供研究和应用。