Yan W X, Dai Y, Zhou Y J, Liu H, Duan S G, Han H H, Chen Y
Key Laboratory of Food Safety Risk Assessment of Ministry of Health,China National Center for Food Safety Risk Assessment,Beijing,People's Republic of China.
Institute of Food Safety and Assessment, Jiangsu Provincial Center for Disease Control and Prevention,Nanjing,People's Republic of China.
Epidemiol Infect. 2015 Apr;143(5):1020-8. doi: 10.1017/S0950268814001599. Epub 2014 Jul 3.
SUMMARY To determine risk factors for sporadic Vibrio parahaemolyticus gastroenteritis, we conducted a population-based case-control study in sentinel hospital surveillance areas of Shanghai and Jiangsu province, China. Seventy-one patients with diarrhoea and confirmed V. parahaemolyticus infections were enrolled, and they were matched with 142 controls for gender, age and residential area. From the multivariable analysis, V. parahaemolyticus infections were associated with antibiotics taken during the 4 weeks prior to illness [odds ratio (OR) 7·6, 95% confidence interval (CI) 1·1–54·4)], frequent eating out (OR 3·3, 95% CI 1·0–10·4), and shellfish consumption (OR 3·4, 95% CI 1·0–11·1), with population-attributable fractions of 0·09, 0·24, and 0·14, respectively. Protective factors included keeping the aquatic products refrigerated (OR 0·4, 95% CI 0·2–1·0) and pork consumption (OR 0·2, 95% CI 0·1–0·9) [corrected] .
摘要 为确定散发性副溶血性弧菌胃肠炎的危险因素，我们在中国上海和江苏省的定点医院监测区域开展了一项基于人群的病例对照研究。纳入了71例腹泻且确诊为副溶血性弧菌感染的患者，并按照性别、年龄和居住地区将他们与142名对照进行匹配。多变量分析显示，副溶血性弧菌感染与病前4周内服用抗生素（比值比[OR] 7.6，95%置信区间[CI] 1.1 - 54.4）、频繁外出就餐（OR 3.3，95% CI 1.0 - 10.4）以及食用贝类（OR 3.4，95% CI 1.0 - 11.1）相关，人群归因分数分别为0.09、0.24和0.14。保护因素包括将水产品冷藏（OR 0.4，95% CI 0.2 - 1.0）和食用猪肉（OR 0.2，95% CI 0.1 - 0.9）[校正后] 。
