Suganya S, Ahila S C, Kumar B Muthu, Kumar M Vasantha
Department of Prosthodontics, Sri Ramasamy Memorial Dental College, Ramapuram, Chennai, Tamil Nadu, India.
Indian J Dent Res. 2014 Mar-Apr;25(2):204-7. doi: 10.4103/0970-9290.135923.
Recent years have been dominated by research in nano science. Dentistry is no exception and there is increased research on nanoparticles in dentistry. Complete dentures increase the carriage of Candida in healthy patients, and the proliferation of C. albicans can be associated with denture-induced stomatitis.
To evaluate the anti-Candida effect of heat cure denture base resins reinforced with Ag° in the ratio of 4:1, 3:1, 2:1 (Groups B, C, and D, respectively) to the weight of denture base resins.
Ag° were synthesized by chemical reduction method, incorporated into the polymer powder according to the ratio for each group, subjected to polymerization and microbial assay was calculated for the reference C. albicans strains by agar diffusion method for the incubation period of 24 h.
Group D showed multifold decrease in the colony-forming units.
The antimicrobial effect of silver could be used vividly in the denture base for immunocompromised and geriatric patients.
近年来纳米科学研究占据主导地位。牙科也不例外，对牙科纳米颗粒的研究日益增多。全口义齿会增加健康患者念珠菌的携带量，白色念珠菌的增殖可能与义齿性口炎有关。
评估按4:1、3:1、2:1比例（分别为B组、C组和D组）与义齿基托树脂重量混合的Ag°增强热固化义齿基托树脂的抗念珠菌作用。
通过化学还原法合成Ag°，按每组比例将其掺入聚合物粉末中，进行聚合反应，并采用琼脂扩散法对白色念珠菌参考菌株进行24小时培养期的微生物检测。
D组菌落形成单位呈数倍减少。
银的抗菌作用可有效应用于免疫功能低下和老年患者的义齿基托。
