Guss W J, Ament M E
Department of Pharmaceutical Services, UCLA Medical Center 90024.
Arch Intern Med. 1989 Jun;149(6):1457-8.
Only three cases of human infection with Oerskovia have been reported. A woman receiving home total parenteral nutrition (TPN) was admitted for catheter-related sepsis caused by Oerskovia. She was discharged on an intravenous regimen of vancomycin, but symptoms recurred her first night home, and she was readmitted. Cultures of the TPN solution and peripheral blood yielded Oerskovia. The patient was successfully treated at home with 5 weeks of intravenous vancomycin therapy (30 mg/kg per day). Home TPN solutions provide an optimal incubation period for growth of microbial contaminants. Although quality control measures appropriate for hospital TPN solutions may be inappropriate for home TPN solutions, no standards currently exist for manufacturers of home TPN solutions. Thus, physicians should inquire about quality controls when choosing a company for home intravenous therapy referrals.
仅报告了3例人类感染奥尔氏菌的病例。一名接受家庭全胃肠外营养（TPN）的女性因奥尔氏菌引起的导管相关败血症入院。她出院时接受静脉注射万古霉素治疗，但回家的第一晚症状复发，她再次入院。TPN溶液和外周血培养出了奥尔氏菌。该患者在家中通过5周的静脉注射万古霉素治疗（每天30mg/kg）成功治愈。家庭TPN溶液为微生物污染物的生长提供了最佳潜伏期。尽管适用于医院TPN溶液的质量控制措施可能不适用于家庭TPN溶液，但目前家庭TPN溶液制造商没有标准。因此，医生在选择家庭静脉治疗转诊公司时应询问质量控制情况。
