Rihs J D, McNeil M M, Brown J M, Yu V L
Department of Microbiology, VA Medical Center, Pittsburgh, Pennsylvania 15240.
J Clin Microbiol. 1990 Sep;28(9):1934-7. doi: 10.1128/jcm.28.9.1934-1937.1990.
Oerskovia species are nocardialike bacteria that have been implicated as pathogens only rarely. These organisms are branched, gram-positive bacilli that are oxidase negative, catalase positive, and non-acid fast. Unlike Nocardia species, these organisms are motile, do not produce aerial mycelia, and possess a cell wall with large amounts of galactose. Colonies are bright yellow and produce branched vegetative hyphae on nutrient agar. A 70-year-old patient undergoing chronic ambulatory peritoneal dialysis for end-stage renal dysfunction developed recurrent peritonitis. Five peritoneal fluid cultures and one catheter specimen obtained over a period of two weeks yielded a gram-positive bacillus; Oerskovia xanthineolytica was isolated from all six cultures. Prolonged systemic therapy with gentamicin and vancomycin was unsuccessful in curing the peritonitis, but the infection resolved following removal of the peritoneal catheter. This is the first reported case of peritonitis associated with this microorganism. A review of previously described Oerskovia infections, most of which were associated with foreign bodies, showed that removal of infected foci was usually necessary for cure.
厄氏菌属是一类类似诺卡氏菌的细菌，极少被认为是病原体。这些微生物是分支的革兰氏阳性杆菌，氧化酶阴性，过氧化氢酶阳性，且抗酸染色阴性。与诺卡氏菌属不同的是，这些微生物具有运动性，不产生气生菌丝，并且拥有含有大量半乳糖的细胞壁。菌落呈亮黄色，在营养琼脂上产生分支的营养菌丝。一名因终末期肾功能不全接受持续非卧床腹膜透析的70岁患者发生了复发性腹膜炎。在两周内采集的5份腹膜液培养物和1份导管标本培养出一株革兰氏阳性杆菌；从所有6份培养物中均分离出解黄嘌呤厄氏菌。使用庆大霉素和万古霉素进行长期全身治疗未能治愈腹膜炎，但在拔除腹膜导管后感染得到缓解。这是首次报道的与这种微生物相关的腹膜炎病例。对先前描述的厄氏菌感染（其中大多数与异物有关）的回顾表明，通常需要清除感染灶才能治愈。
