Holbrook Joseph R, Cuffe Steven P, Cai Bo, Visser Susanna N, Forthofer Melinda S, Bottai Matteo, Ortaglia Andrew, McKeown Robert E
Centers for Disease Control and Prevention, Atlanta, GA, USA
University of Florida College of Medicine-Jacksonville, FL, USA.
J Atten Disord. 2016 Jan;20(1):11-20. doi: 10.1177/1087054714539997. Epub 2014 Jul 3.
To examine ADHD symptom persistence and factors associated with elevated symptom counts in a diverse, longitudinal community-based sample.
Parents reported demographics and completed a diagnostic interview repeatedly over a 6-year period. At Time 1, 481 interviews were completed about children (5-13 years); all participants were invited to four annual follow-up interviews, and 379 (79%) completed at least one. Inattentive (IA) and hyperactive-impulsive (HI) symptom counts were modeled with logistic quantile regression, while accounting for study design complexities.
The prevalence of seven IA symptoms remained stable from early childhood through late adolescence. The prevalence of eight HI symptoms decreased by more than half over time. After demographic adjustment, the upper quartile of HI symptom counts decreased with age (p < .01). High HI symptom counts persisted more among those with high IA symptom counts (p = .05).
This study further characterizes and provides insights into ADHD symptom trajectory through adolescence.
在一个多样化的、基于社区的纵向样本中，研究注意力缺陷多动障碍（ADHD）症状的持续性以及与症状计数升高相关的因素。
家长报告人口统计学信息，并在6年期间多次完成诊断性访谈。在时间1，完成了481次关于儿童（5至13岁）的访谈；所有参与者都被邀请参加四次年度随访访谈，379人（79%）至少完成了一次。使用逻辑分位数回归对注意力不集中（IA）和多动冲动（HI）症状计数进行建模，同时考虑研究设计的复杂性。
从幼儿期到青春期后期，七种IA症状的患病率保持稳定。随着时间的推移，八种HI症状的患病率下降了一半以上。经过人口统计学调整后，HI症状计数的上四分位数随年龄下降（p <.01）。高IA症状计数的人群中，高HI症状计数持续存在的情况更多（p =.05）。
本研究进一步描述了ADHD症状在青春期的轨迹，并提供了相关见解。
