Pati Abhishek Ranjan, Kr Vijayalakshmi, Singh Chandravir
Senior Lecturer, Department of Oral Medicine & Radiology, Institute of Dental Sciences & SUM Hospital , Bhubaneshwar, Odisha, India .
Professor and HOD, Department of Oral Medicine & Radiology, Government Dental College and Research Institute , Bangalore, India .
J Clin Diagn Res. 2014 May;8(5):ZD13-5. doi: 10.7860/JCDR/2014/7511.4358. Epub 2014 May 15.
Brown's tumour is an uncommon focal giant cell lesion which arises as a result of the effect of increased parathyroid hormone on bone tissues in hyperparathyroidism. The mandible is the predominantly affected site in the maxillofacial area and a maxillary involvement is rare. The severity of the lesion, caused by a Brown's tumour, may lead to evident osteolysis and gross deformity in the maxillofacial region, which suggests the need for making an early diagnosis and giving prompt treatment. We are reporting a male patient who presented with a massive painful swelling in the right maxilla as the first manifestation of primary hyperparathyroidism, caused by a parathyroid adenoma.
棕色瘤是一种罕见的局灶性巨细胞病变,由甲状旁腺功能亢进时甲状旁腺激素水平升高对骨组织的作用所致。下颌骨是颌面部最常受累的部位,上颌骨受累罕见。由棕色瘤引起的病变严重程度可导致颌面部明显的骨质溶解和严重畸形,这表明需要早期诊断并及时治疗。我们报告一例男性患者,其首发表现为右上颌骨巨大疼痛性肿胀,病因是甲状旁腺腺瘤导致的原发性甲状旁腺功能亢进。