van Dam I, Delemarre B, Hopman J, de Boo T, Uiterwaal C, Fast J, van Oort A, van der Werf T, Daniëls O
Interuniversity Cardiology Institute, Utrecht, The Netherlands.
J Clin Ultrasound. 1989 Jun;17(5):339-44. doi: 10.1002/jcu.1870170506.
To investigate the relationship between age-related blood flow velocity and heart rate in the left ventricular inflow tract, we studied 118 healthy volunteers (age greater than 15 years). The maximal velocity (Vmax) of the transmitral diastolic flow during early ventricular filling (E) and during filling due to atrial contraction (A) was measured at 3 sites in the left ventricle with pulsed Doppler echocardiography. At all these sites a significant positive correlation was found between the VmaxA and the EA ratio and the interaction of heart rate and age. VmaxA increases if age and heart rate increase. The influence of the interaction of age and heart rate on VmaxA is most pronounced near the mitral annulus. VmaxA is only related to age and decreases with advancing age. Our observations contribute to the explanation of the more important role of the atrial contraction in the elderly.
为了研究左心室流入道中与年龄相关的血流速度和心率之间的关系，我们对118名健康志愿者（年龄大于15岁）进行了研究。使用脉冲多普勒超声心动图在左心室的3个部位测量了心室早期充盈（E）和心房收缩期充盈（A）时二尖瓣舒张期血流的最大速度（Vmax）。在所有这些部位，发现VmaxA与E/A比值以及心率与年龄的相互作用之间存在显著正相关。如果年龄和心率增加，VmaxA会增加。年龄和心率的相互作用对VmaxA的影响在二尖瓣环附近最为明显。VmaxA仅与年龄有关，并随年龄增长而降低。我们的观察结果有助于解释心房收缩在老年人中更重要的作用。
