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一组因持续症状寻求物理治疗的急性挥鞭样损伤相关疾病患者慢性残疾的危险因素。

Risk factors for chronic disability in a cohort of patients with acute whiplash associated disorders seeking physiotherapy treatment for persisting symptoms.

作者信息

Williamson Esther, Williams Mark A, Gates Simon, Lamb Sarah E

机构信息

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, United Kingdom.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, United Kingdom.

出版信息

Physiotherapy. 2015 Mar;101(1):34-43. doi: 10.1016/j.physio.2014.04.004. Epub 2014 Apr 26.

DOI:10.1016/j.physio.2014.04.004
PMID:24996567
Abstract

OBJECTIVES

(1) To identify risk factors for chronic disability in people with acute whiplash associated disorders (WAD). (2) To estimate the impact of the numbers of risk factors present.

DESIGN

Prospective cohort study. Data were collected, on average, 32 days after injury (SD=10.9) and 12 months later. Baseline measures of pain, disability, neck movement, psychological and behavioural factors were independent variables and chronic disability at 12 months was the dependent variable in a multivariable logistic regression analysis.

SETTING

National Health Service physiotherapy departments.

PARTICIPANTS

Participants (n=599) with symptoms 3 weeks after injury, self-referred to physiotherapy as part of a randomised controlled trial. 430 (72%) participants provided complete data for this analysis.

MAIN OUTCOME MEASURES

Chronic disability based on Neck Disability Index scores.

RESULTS

136 (30%) participants developed chronic disability. High baseline disability (OR 3.3, 95% CI 1.97 to 5.55), longer predicted recovery time (OR 2.4, 95% CI 1.45 to 3.87), psychological distress (OR 1.9, 95%CI 1.05 to 3.51), passive coping (OR 1.8, 95% CI 1.07 to 2.97) and greater number of symptoms (OR 1.7, 95% CI 1.07 to 2.78) were associated with chronic disability. One risk factor resulted in 3.5 times the risk (95% CI 1.04 to 11.45) of chronic disability but this risk increased to 16 times (95%CI 5.36 to 49.27) in those with four or five risk factors.

CONCLUSION

Baseline disability had the strongest association with chronic disability but psychological and behavioural factors were also important. Treatment strategies should reflect this which may require a change to current physiotherapy approaches for acute WAD. The number of risk factors present should be considered when evaluating potential for poor outcome.

摘要

目的

(1)确定急性挥鞭样损伤相关疾病(WAD)患者慢性残疾的风险因素。(2)评估存在的风险因素数量的影响。

设计

前瞻性队列研究。平均在受伤后32天(标准差=10.9)和12个月后收集数据。疼痛、残疾、颈部活动、心理和行为因素的基线测量值为自变量,12个月时的慢性残疾为多变量逻辑回归分析中的因变量。

设置

国民健康服务物理治疗科室。

参与者

受伤3周后出现症状的参与者(n=599),作为随机对照试验的一部分自行转诊至物理治疗科室。430名(72%)参与者提供了完整数据用于本分析。

主要结局指标

基于颈部残疾指数评分的慢性残疾。

结果

136名(30%)参与者出现慢性残疾。高基线残疾(比值比3.3,95%置信区间1.97至5.55)、较长的预测恢复时间(比值比2.4,95%置信区间1.45至3.87)、心理困扰(比值比1.9,95%置信区间1.05至3.51)、消极应对(比值比1.8,95%置信区间1.07至2.97)和更多的症状数量(比值比1.7,95%置信区间1.07至2.78)与慢性残疾相关。一个风险因素导致慢性残疾风险增加3.5倍(95%置信区间1.04至11.45),但在有四个或五个风险因素的参与者中,这一风险增加到16倍(95%置信区间5.36至49.27)。

结论

基线残疾与慢性残疾的关联最强,但心理和行为因素也很重要。治疗策略应反映这一点,这可能需要改变当前针对急性WAD的物理治疗方法。在评估不良结局可能性时应考虑存在的风险因素数量。

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