Kucera Jennifer N, Coley Ian, O'Hara Sara, Kosnik Edward J, Coley Brian D
Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA,
Pediatr Radiol. 2015 Feb;45(2):211-6. doi: 10.1007/s00247-014-3110-1. Epub 2014 Jul 5.
Although spinal cord tethering is known to be associated with certain clinical syndromes and cutaneous stigmata, its incidence in healthy infants with simple sacral dimples has not been thoroughly evaluated.
Our objective was to determine the frequency of tethered cord in otherwise healthy patients with simple sacral dimples.
We reviewed the lumbar spine US reports of all healthy neonates referred for a simple sacral dimple during a 12-year period at two children's hospitals. A sonogram was considered abnormal for a conus medullaris terminating below the L2-L3 disc space, decreased conus or nerve root motion, an abnormal filum terminale, or for the presence of an intraspinal mass, osseous dysraphism, or a sinus leading to the thecal sac. The medical records of patients with abnormal screening sonograms were reviewed to determine the final clinical outcome.
During the study period 3,991 infants underwent screening sonography. Of these, 107 were excluded because of the presence of other medical conditions. Of the remaining 3,884 healthy infants, 133 (3.4%) had an abnormal sonogram. Five (0.13%) of these infants were lost to follow-up; 52 subsequently had normal follow-up imaging; 49 had a low conus without other signs of tethering; 18 had a fatty filum; 2 had decreased conus motion; 2 had both a low conus and a fatty filum. None of these infants underwent surgery. Only the remaining 5/3,884 (0.13%) infants underwent surgical intervention (95% CI: 0-0.27%), and 4/5 were found to have a tethered cord intraoperatively.
The risk of significant spinal malformations in asymptomatic, healthy infants with an isolated simple sacral dimple is exceedingly low.
虽然已知脊髓栓系与某些临床综合征和皮肤体征有关,但其在单纯骶部酒窝的健康婴儿中的发生率尚未得到充分评估。
我们的目的是确定单纯骶部酒窝的其他方面健康的患者中脊髓栓系的频率。
我们回顾了两家儿童医院在12年期间所有因单纯骶部酒窝而转诊的健康新生儿的腰椎超声报告。若脊髓圆锥终止于L2-L3椎间盘间隙以下、圆锥或神经根运动减弱、终丝异常、或存在椎管内肿块、骨发育异常或通向硬膜囊的窦道,则超声检查被认为异常。对筛查超声异常的患者的病历进行回顾以确定最终临床结果。
在研究期间,3991名婴儿接受了筛查超声检查。其中,107名因存在其他疾病而被排除。在其余3884名健康婴儿中,133名(3.4%)超声检查异常。这些婴儿中有5名(0.13%)失访;52名随后随访影像正常;49名脊髓圆锥较低但无其他栓系迹象;18名有脂肪终丝;2名圆锥运动减弱;2名脊髓圆锥较低且有脂肪终丝。这些婴儿均未接受手术。只有其余5/3884名(0.13%)婴儿接受了手术干预(95%可信区间:0-0.27%),其中4/5在术中发现有脊髓栓系。
无症状、健康且仅有单纯骶部酒窝的婴儿发生严重脊柱畸形的风险极低。