Yuan Li, Ou Yuan, Liao Qinxiang, Gui Juan, Bai Xue, Ge Jianye, Ye Jian, Zhang Lin
West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, Sichuan 610041, PR China; Key Laboratory of Evidence Science (China University of Political Science and Law), Ministry of Education, China.
Institute of Forensic Science, Ministry of Public Security, Beijing 100038, PR China.
Leg Med (Tokyo). 2014 Sep;16(5):314-8. doi: 10.1016/j.legalmed.2014.05.008. Epub 2014 Jun 4.
A total of 38 autosomal Short Tandem Repeat (STR) loci (i.e., D5S818, D21S11, D7S820, CSF1P0, D2S1338, D3S1358, vWA, D8S1179, D16S539, Penta E, TPOX, TH01, D19S433, D18S51, FGA, D6S1043, D13S317, D12S391, D6S474, D12ATA63, D22S1045, D10S1248, D1S1677, D11S4463, D1S1627, D3S4529, D2S441, D6S1017, D4S2408, D17S1301, D1GATA113, D18S853, D20S482, D14S1434, D9S1122, D2S1776, D10S1435, D5S2500) were analyzed in the She population from Fujian Province of China with 154 unrelated individuals. The results show these 38 STR loci have high or medium power of discrimination and probabilities of exclusion. The Hardy-Weinberg Equilibrium of each locus and Linkage Disequilibrium among these loci were tested. The genetic distances (i.e., Fst) among the She population and other Chinese populations were estimated. In conclusion, these loci are very useful for forensic applications, especially kinship analysis, in the She population of this region.
对来自中国福建省的154名无亲缘关系的畲族个体，分析了总共38个常染色体短串联重复序列（STR）基因座（即D5S818、D21S11、D7S820、CSF1P0、D2S1338、D3S1358、vWA、D8S1179、D16S539、五核苷酸重复序列E、TPOX、TH01、D19S433、D18S51、FGA、D6S1043、D13S317、D12S391、D6S474、D12ATA63、D22S1045、D10S1248、D1S1677、D11S4463、D1S1627、D3S4529、D2S441、D6S1017、D4S2408、D17S1301、D1GATA113、D18S853、D20S482、D14S1434、D9S1122、D2S1776、D10S1435、D5S2500）。结果表明，这38个STR基因座具有高或中等的鉴别力和排除概率。对每个基因座的哈迪-温伯格平衡以及这些基因座之间的连锁不平衡进行了检验。估计了畲族群体与其他中国群体之间的遗传距离（即Fst）。总之，这些基因座对该地区畲族群体的法医应用，尤其是亲缘关系分析非常有用。
